College football Week 5 odds are available at online sportsbooks. This week continues with a packed Saturday of wall-to-wall action.
Top matchups at college football betting sites include Georgia vs. Alabama in a showdown of SEC powerhouses. Louisville will visit Notre Dame, and Wisconsin will be on the road against USC for a Big Ten battle.
Read on for a look at Week 5 games and the latest odds at legal online sports betting sites.
College football Week 5 odds: Spreads, moneylines, totals
College football Week 5 spreads, lines, totals
| Matchup | Spread | Moneyline | Over/under |
| Oklahoma at Auburn | Oklahoma -1.5 | OK -104/AUB -115 | 44.5 |
| Oklahoma State at Kansas State | Kansas State -5.5 | OKST +172/KST -210 | 57.5 |
| Wisconsin at USC | USC -14.5 | WIS +470/USC -670 | 50.5 |
| Fresno State at UNLV | UNLV -2.5 | FRES +110/UNLV -132 | 49.5 |
| Louisville at Notre Dame | Notre Dame -6.5 | LOU +205/ND -255 | 46.5 |
| North Carolina at Duke | Duke -2.5 | UNC +108/DUKE -130 | 55.5 |
| Georgia at Alabama | Georgia -1.5 | UGA -118/ALA -102 | 50.5 |
| Arizona at Utah | Utah -9.5 | AZ +270/UT -345 | 47.5 |
| Ohio State at Michigan State | Ohio State -23.5 | OSU -3500/MSU +1280 | 47.5 |
Explore more college football
Looking for more information when it comes to the 2024 college football season? Below, we cover some key resources for betting on more than just Week 5.
College football Week 5 odds and analysis
Oklahoma vs. Auburn
- Spread: Oklahoma Oklahoma Sooners +1 on Consensus, Auburn Auburn Tigers -1 on Consensus
- Moneyline: Oklahoma Oklahoma Sooners +100 on Consensus, Auburn Auburn Tigers -120 on Consensus
- Over/under: 42.5 on FanDuel
Now part of the SEC after the latest round of college football conference realignment, the Sooners are in the midst of beginning new rivalries. These programs have only met twice, with Oklahoma winning both games. Auburn is 2-2 following a loss to Arkansas. The Tigers are turning back to Payton Thorne under center after Hank Brown got the nod in the last two games. Oklahoma dropped to 3-1 with a loss to Tennessee.
Oklahoma State vs. Kansas State
- Spread: Oklahoma State Oklahoma State Cowboys +6 on DraftKings, Kansas State Kansas State Wildcats -6 on DraftKings
- Moneyline: Oklahoma State Oklahoma State Cowboys +175 on Consensus, Kansas State Kansas State Wildcats -215 on Consensus
- Over/under: 57.5 on FanDuel
The Big 12 chase is expected to be competitive throughout the campaign. Oklahoma State and Kansas State are currently jockeying for second in odds to win the conference, behind Utah. The Cowboys and Wildcats have matching 3-1 records and are both looking to rebound from losses. Oklahoma State has won four of the last five in this series, taking last season’s meeting by a score of 29-21.
Wisconsin vs. USC
- Spread: Wisconsin Wisconsin Badgers +14 on DraftKings, USC USC Trojans -14 on DraftKings
- Moneyline: Wisconsin Wisconsin Badgers +425 on Consensus, USC USC Trojans -575 on Consensus
- Over/under: 58.5 on FanDuel
Wisconsin heads out west for a Big Ten showdown with USC. Last time out, the Badgers were hammered by visiting Alabama 42-10 to fall to 2-1. The Trojans fell to 2-1 with a 27-24 loss at Michigan on Saturday in the program’s first game in its new conference. This will be the first meeting of the two programs since 2015, a 23-21 victory for Wisconsin.
Fresno State vs. UNLV
- Spread: Fresno State Fresno State Bulldogs +2.5 on FanDuel, UNLV UNLV Rebels -2.5 on FanDuel
- Moneyline: Fresno State Fresno State Bulldogs +110 on FanDuel, UNLV UNLV Rebels -132 on FanDuel
- Over/under: 72.5 on FanDuel
Early odds to win the Mountain West Conference have Boise State as a heavy favorite. UNLV and Fresno State hold down the second and third spots on the board. The Bulldogs are 3-1, while the Rebels are 3-0. Fresno State has won six straight meetings between these schools, including a 31-24 victory last season. UNLV starting QB Matthew Sluka has announced that he’s sitting out the remainder of the season due to an NIL dispute. The spread for this one has been active as a result.
Louisville vs. Notre Dame
- Spread: Louisville Louisville Cardinals +6.5 on BetRivers, Notre Dame Notre Dame Fighting Irish -6.5 on BetRivers
- Moneyline: Louisville Louisville Cardinals +215 on BetRivers, Notre Dame Notre Dame Fighting Irish -230 on FanDuel
- Over/under: 48.5 on FanDuel
Since an upset loss to Northern Illinois, Notre Dame has ripped off two straight in convincing fashion. The Fighting Irish took down Purdue 66-7 and followed with a 28-3 victory over Miami-Ohio. Louisville moved to 3-0 with a 31-19 win over visiting Georgia Tech on Saturday. The two schools met last season, with the Cardinals picking up a 33-20 win.
North Carolina vs. Duke
- Spread: North Carolina North Carolina Tar Heels +0.5 on Consensus, Duke Duke Blue Devils -0.5 on Consensus
- Moneyline: North Carolina North Carolina Tar Heels -110 on Consensus, Duke Duke Blue Devils -110 on Consensus
- Over/under: 47.5 on Consensus
The latest edition of this ACC rivalry will see North Carolina take a quick trip to square off with Duke. The Tar Heels are 3-1 following a 70-50 loss to James Madison in a game in which they were -11.5 favorites. The Blue Devils are 4-0 following a win over Middle Tennessee. The Tar Heels have won five in a row over Duke, picking up a 47-45 victory last season in an overtime thriller.
Georgia vs. Alabama
- Spread: Georgia Georgia Bulldogs -1 on BetRivers, Alabama Alabama Crimson Tide +2 on DraftKings
- Moneyline: Georgia Georgia Bulldogs -117 on BetRivers, Alabama Alabama Crimson Tide +104 on FanDuel
- Over/under: 65.5 on BetRivers
It’s a battle of SEC heavyweights under the bright lights at Bryant-Denny Stadium. Georgia and Alabama are two of the top favorites in CFP odds to win it all. Alabama defeated Georgia 27-24 in last season’s SEC title game, ending the Bulldogs’ playoff hopes. The two squads had last week off and are each 3-0 on the season.
Arizona vs. Utah
- Spread: Arizona Arizona Wildcats +7.5 on DraftKings, Utah Utah Utes -7.5 on DraftKings
- Moneyline: Arizona Arizona Wildcats +230 on Consensus, Utah Utah Utes -285 on Consensus
- Over/under 47 on Consensus
These two former Pac-12 programs have taken their rivalry to the Big 12. Utah has kicked off its season at 4-0 and remains the favorite to win the conference. Arizona is 2-1 following a loss to Kansas State and had last week off. The Wildcats took last season’s meeting 42-18, snapping a run of six straight wins for the Utes between these conference foes.
Ohio State at Michigan State
- Spread: Ohio State Ohio State Buckeyes -23.5 on FanDuel, Michigan State Michigan State Spartans +23.5 on FanDuel
- Moneyline: Ohio State Ohio State Buckeyes -2500 on Consensus, Michigan State Michigan State Spartans +1145 on Consensus
- Over/under: 46.5 on FanDuel
Ohio State is a perfect 3-0 to begin the season and among the top favorites to win the national title. On Saturday, the Buckeyes defeated visiting Marshall 49-14. Michigan State dropped to 3-1 with a road loss to Boston College, getting the cover as a +4.5 underdog. Ohio State has won eight straight over the Spartans, taking last season’s meeting by a score of 38-3.
College football Week 5 odds tracker
| Matchup | Current Spread | Sept. 28 Odds | Sept. 27 Odds | Sept. 26 Odds | Sept. 25 Odds | Sept. 24 Odds | Sept. 23 Odds | Sept. 22 Odds | Opening Spread |
| Oklahoma at Auburn | Oklahoma Oklahoma Sooners +1 on Consensus | Oklahoma -1.5 | Oklahoma -1.5 | Oklahoma -2.5 | Oklahoma -2.5 | Oklahoma -2.5 | Oklahoma -2.5 | Oklahoma -3.5 | Oklahoma -2.5 |
| Oklahoma State at Kansas State | Kansas State Kansas State Wildcats -6 on DraftKings | Kansas State -5.5 | Kansas State -4.5 | Kansas State -5.5 | Kansas State -4.5 | Kansas State -5.5 | Kansas State -6.5 | Kansas State -3.5 | Kansas State -3.5 |
| Wisconsin at USC | USC USC Trojans -14 on DraftKings | USC -14.5 | USC -14.5 | USC -15.5 | USC -15.5 | USC -15.5 | USC -14.5 | USC -14.5 | USC -4.5 |
| Fresno State at UNLV | UNLV UNLV Rebels -2.5 on FanDuel | UNLV -2.5 | UNLV -2.5 | UNLV -1.5 | Fresno State -1.5 | UNLV -3.5 | UNLV -3.5 | UNLV -4.5 | UNLV -3 |
| Louisville at Notre Dame | Notre Dame Notre Dame Fighting Irish -6.5 on BetRivers | Notre Dame -6.5 | Notre Dame -6.5 | Notre Dame -6.5 | Notre Dame -6.5 | Notre Dame -6.5 | Notre Dame -4.5 | Notre Dame -3.5 | Notre Dame -3.5 |
| North Carolina at Duke | Duke Duke Blue Devils +1.5 on FanDuel | Duke -2.5 | Duke -2.5 | Duke -2.5 | Duke -2.5 | Duke -2.5 | Duke -2.5 | Duke -2.5 | North Carolina -1.5 |
| Georgia at Alabama | Georgia Georgia Bulldogs -1 on BetRivers | Georgia -1.5 | Georgia -1.5 | Georgia -2.5 | Georgia -2.5 | Georgia -2.5 | Georgia -2.5 | Georgia -2.5 | Georgia -2.5 |
| Arizona at Utah | Utah Utah Utes -7.5 on Consensus | Utah -9.5 | Utah -7.5 | Utah -11.5 | Utah -11.5 | Utah -12.5 | Utah -12.5 | Utah -9.5 | Utah -9.5 |
| Ohio State at Michigan State | Ohio State Ohio State Buckeyes -23.5 on FanDuel | Ohio State -23.5 | Ohio State -23.5 | Ohio State -23.5 | Ohio State -23.5 | Ohio State -24.5 | Ohio State -24.5 | Ohio State -24.5 | Ohio State -24.5 |
