The NFL’s stretch run continues in a Week 12 that sees a season-high six teams on bye. However, there are still plenty of intriguing matchups as clubs begin jockeying for postseason positioning in earnest.
Below, LSR has the latest odds from top sportsbooks, along with a quick-hitting NFL betting preview for each Week 12 game.
NFL Week 12 odds: Spreads, moneylines, totals
NFL Week 12 opening spreads, lines, totals
| Game | Point spread | Moneyline | Total |
|---|---|---|---|
| Pittsburgh Steelers at Cleveland Browns | Steelers -3.5 | Steelers -195 Browns +170 | 38.5 |
| Kansas City Chiefs at Carolina Panthers | Chiefs -11.5 | Chiefs -590 Panthers +500 | 41.5 |
| Tampa Bay Buccaneers at New York Giants | Buccaneers -5 | Buccaneers -215 Giants +185 | 42 |
| Detroit Lions at Indianapolis Colts | Lions -7 | Lions -365 Colts +320 | 50.5 |
| Tennessee Titans at Houston Texans | Texans -7.5 | Titans +320 Texans -370 | 41.5 |
| New England Patriots at Miami Dolphins | Dolphins -7.5 | Patriots +300 Dolphins -370 | 45.5 |
| Dallas Cowboys at Washington Commanders | Commanders -10 | Cowboys +400 Commanders -500 | 45.5 |
| Minnesota Vikings at Chicago Bears | Vikings -3.5 | Vikings -175 Bears +155 | 40 |
| Denver Broncos at Las Vegas Raiders | Broncos -4.5 | Broncos -220 Raiders +205 | 41 |
| Arizona Cardinals at Seattle Seahawks | Seahawks -1 | Cardinals -105 Seahawks -112 | 47.5 |
| San Francisco 49ers at Green Bay Packers | Packers -1 | 49ers +104 Packers -120 | 47.5 |
| Philadelphia Eagles at Los Angeles Rams | Eagles -2.5 | Eagles -150 Rams +132 | 48 |
| Baltimore Ravens at Los Angeles Chargers | Ravens -2 | Ravens -130 Chargers +120 | 47.5 |
NFL Week 12 game odds and analysis
Pittsburgh Steelers (-4) at Cleveland Browns (+4)
The Steelers put together a statement win that further cemented their perch atop the AFC North. Pittsburgh’s 18-16 victory over Baltimore featured another balanced offensive showing and pushed Russell Wilson’s record as starter to 4-0.
The Browns were better on offense than during their pre-bye loss to the Chargers, but Cleveland’s defense couldn’t keep up with a short-handed Saints offense in a 35-14 loss. Jameis Winston still threw for almost 400 yards, but the defensive matchup goes up a few notches against their AFC North rival.
The Steelers’ 8-2 season record is mirrored in their mark against the spread as well, tying Pittsburgh with Detroit for tops in the league. That includes a 4-1 tally against the number on the road.
In contrast, the Browns are 3-7 ATS overall, including an ugly 1-4 at home.
The game has opened with a projected total of 36.5 points.
Detroit Lions (-8) at Indianapolis Colts (+8)
The Lions pushed their record to 9-1 with a 52-6 shellacking of the Jaguars in Week 11. Jared Goff threw for over 400 yards and four touchdowns as Detroit’s offense once again resembled an unstoppable juggernaut.
The Colts, meanwhile, squeaked out a 28-27 victory over the Jets to stay alive in the AFC postseason picture. Anthony Richardson looked significantly improved in his return to the starting job while completing 66.7% of his passes.
The Lions are a formidable 4-1 against the spread as a road team, but the Colts mirror that record versus the spread as a home team.
This game opened with an over/under line of 50.5 points.
Kansas City Chiefs (-11) at Carolina Panthers (+11)
The defending champion Chiefs finally saw their record blemished in a 30-21 defeat at the hands of the Bills on Sunday. Patrick Mahomes was more harassed than usual, taking two sacks and tossing a pair of picks as well. KC’s defense was also more generous than usual in what was potentially a preview of yet another Mahomes-Josh Allen postseason showdown.
The Panthers were off in Week 10 after a win over the Giants in Germany. There are cautious signs of optimism in Carolina regarding Bryce Young, who looks like he may have benefited mentally from his early-season benching. The Panthers have a two-game winning streak and will naturally have a rest advantage in this spot, but they unsurprisingly remain massive home underdogs.
The Chiefs have played plenty of close games, so a 5-5 mark against the spread that’s in contrast to their 9-1 season record isn’t surprising. However, they’re a winning team against the number on the road (3-2).
The Panthers have had a rough go of it overall despite the recent surge, so their 1-3 record versus the number at home tracks with their season.
The game has opened with a projected total of 41.5 points.
Tampa Bay Buccaneers (-5) at New York Giants (+5)
The Buccaneers got a much-needed bye in Week 11 following a fourth straight loss in Week 10. Tampa Bay’s last three defeats have all been by single digits and have come by a total of 14 points, commendable in a way considering the key absences at receiver. One of those is likely to come to an end ahead of this game – Mike Evans is thought to have a good chance of returning from his hamstring injury.
The Giants have some personnel movement of their own coming out of their Week 10 bye. Daniel Jones has been benched and booted all the way to No. 3 on the depth chart, with Tommy DeVito and Drew Lock now occupying the top QB spots. New York certainly isn’t bereft of skill-position talent and DeVito thrived for stretches last season, adding some intrigue to this clash.
The Bucs have been very competitive on the road as evidenced in part by their 3-1 ATS mark in that split. The Giants are just 1-4 versus the number at home and three double-digit losses there.
The game has opened with a projected total of 42 points.
Detroit Lions (-8) at Indianapolis Colts (+8)
The Lions pushed their record to 9-1 with a 52-6 shellacking of the Jaguars in Week 11. Jared Goff threw for over 400 yards and four touchdowns as Detroit’s offense once again resembled an unstoppable juggernaut.
The Colts squeaked out a 28-27 victory over the Jets to stay alive in the AFC postseason picture. Anthony Richardson looked significantly improved in his return to the starting job while completing 66.7 percent of his passes.
The Lions are a formidable 4-1 against the spread as a road team, but the Colts mirror that record versus the number as a home team.
The game has opened with a projected total of 50.5 points.
Tennessee Titans (+7.5) at Houston Texans (-7.5)
The Titans fell to 2-8 with a home loss to the Vikings in Week 11. Will Levis should continue as the starting quarterback after a serviceable performance, but he propped up his numbers with a 98-yard touchdown pass courtesy of a blown coverage.
The Texans take the field Monday night against the Cowboys to close out Week 11. Houston is getting Nico Collins back from a five-game absence due to a hamstring injury, which should help restore the offense’s luster. The Texans have dropped three of their last four, although these defeats came with Collins out and were by a combined 13 points.
The Titans are poor against the spread as well, with a 1-4 mark on the road. The Texans are 2-2-1 ATS at home.
The game has opened with a projected total of 41.5 points.
New England Patriots (+7) at Miami Dolphins (-7)
The Patriots continued to show plenty of signs of life under Drake Maye versus the visiting Rams in Week 11. However, New England dropped a 28-22 decision when Maye was intercepted late. The Pats’ defense continues to be the biggest albatross for New England, giving up 402 yards at 7.9 yards per play.
The Dolphins picked up a relatively unsurprising 34-19 win over the visiting Raiders on Sunday. Tua Tagovailoa continued to pump life into Miami’s attack and Tyreek Hill inched closer to that long-overdue Cheetah-like performance with a 7-61-1 line.
Miami prevailed in the first meeting between these teams back in Week 5, albeit by a thin 15-10 margin with Tyler Huntley running the offense.
The Patriots have held their own on the road despite often being overmatched – New England is 3-2 ATS when traveling. Then, the Dolphins’ upheaval at the QB position this season has helped produce a 1-4 mark against the spread at home, with Miami’s first win in that regard coming vs. the Raiders.
The game has opened with a projected total of 46 points.
Dallas Cowboys (+10) at Washington Commanders (-10)
The Cowboys will aim to avoid a fifth straight loss in Monday night’s home date against the Texans. Dallas will open the game with Cooper Rush at quarterback, but it could well be Trey Lance under center by game’s end if Rush is as ineffective as during a Week 10 loss to the Eagles (45 passing yards, two lost fumbles).
The Commanders will have extra rest for this rivalry game following a TNF loss to the Eagles to open Week 11. Washington has consecutive losses at the hands of the Pennsylvania teams, but this matchup represents a major downgrade in caliber of competition for Jayden Daniels and co.
The Cowboys are 2-3 ATS on the road while the Commanders have been very impressive with a 4-1 home record against the number and a ATS +/- of +8.3 points.
The game has opened with a projected total of 45.5 points.
Minnesota Vikings (-4) at Chicago Bears (+4)
The Vikings’ offense showed signs of life again after a 12-point afternoon in Week 10 against the Jaguars. Minnesota recorded a 23-13 victory over a tough Titans defense on the road, and Sam Darnold managed to stay away from any interceptions while accounting for three total TDs as the Vikes moved to 8-2.
The Bears — and Caleb Williams in particular — looked much more coherent on offense in their first game under interim coordinator Thomas Brown. Williams put Chicago in position for a game-winning field-goal attempt with a trio of clutch completions to Rome Odunze and Keenan Allen before Cairo Santos’ kick was blocked.
This is another strength vs. strength matchup when it comes to the spread — the Vikes are 3-2 ATS on the road, while the Bears, for all their woes, are 4-1 against the spread at Soldier Field.
This game opened with a total of 40.5 points.
Denver Broncos (-5) at Las Vegas Raiders (+5)
The Broncos and Bo Nix continued to demonstrate they could well be a legitimate postseason contender with a 38-6 drubbing of the Falcons. Nix threw for a career-high 307 yards and four touchdowns as he continued to demonstrate a mastery of Sean Payton’s system, while the team’s elite defense completely neutralized a talented Atlanta attack.
The Raiders dropped a 34-19 decision to the Dolphins coming out of Las Vegas’ Week 10 bye. Gardner Minshew and Brock Bowers (13 catches, 126 yards) did put on an offensive showcase, but Vegas continues to suffer from a moribund running game and inconsistent defense.
The first installment of the season series went the Broncos’ way – Denver recorded a 34-18 win at Empower Field back in Week 5.
Another impressive aspect of the Broncos’ season is their body of work against the spread on the road – Denver is 5-1 in that split. The Raiders are an even 2-2 ATS at home and 4-3 vs. the number overall following a loss.
The game has opened with a projected total of 41.5 points.
San Francisco 49ers (+1.5) at Green Bay Packers (-1.5)
The 49ers’ rare brush with ordinary persisted in Week 11. San Francisco allowed Geno Smith to march the Seahawks down for a game-winning drive in a 20-17 defeat that dropped Kyle Shanahan’s squad to 5-5.
The Packers came out of their bye with a healthier Jordan Love and squeaked by the Bears for a 20-19 victory on a blocked field goal as time expired. A Green Bay squad that’s now 7-3 continues to win with a balanced offensive attack and solid defense, but it’s worth noting that two of the Pack’s three losses have come at Lambeau Field.
The Niners have not fared well versus the spread when traveling, mustering a 1-3 ATS road record. The Packers are 2-3 against the spread at home.
This game opened with an over/under line of 47.5 points.
Arizona Cardinals (+1) at Seattle Seahawks (-1)
The Cardinals come out of a Week 11 bye with no shortage of momentum. Arizona has won four straight overall, with the last two victories by a combined 45 points over the Bears and Jets.
The Seahawks got a desperately needed win and did so against a marquee division opponent in Week 11. Geno Smith led a valiant late-game drive that he capped off with a TD run to seal a 20-17 comeback victory on the road against the 49ers. Seattle is now 5-5, and this game against the division-leading Cardinals is the first of two versus Arizona in the next three weeks.
The Cardinals are an impressive 3-1 against the spread as a road team, while the Seahawks’ infamous 12th Man hasn’t been much help to Mike Macdonald’s squad in any sense this season — Seattle is 2-4 straight up at home and 1-5 ATS.
This game opened with a line of 47.5 total points.
Philadelphia Eagles (-3) at Los Angeles Rams (+3)
The Eagles managed a key division win when they toppled the Commanders by a 26-18 score to open the Week 11 slate Thursday night. Philly’s offense was a study in balance and was clicking on all cylinders; Jalen Hurts threw for 221 yards while Saquon Barkley rushed for 146 and a pair of scores.
The Rams pulled off an impressive feat by traveling cross country on a short week and upending the Patriots, 28-22. Matthew Stafford was in vintage form with 295 yards and four touchdowns, with the Puka Nacua-Cooper Kupp duo accounted for 229 of those yards and three of those scores.
The Eagles are quite the juggernaut against the spread on the road. Philly is a co-NFL-best 4-1 ATS when traveling while boasting a league-high ATS +/- of +10.6 points in that split. Yet, they’re curiously 0-2 against the number when playing with a rest advantage.
The Rams, in contrast, are only 2-3 against the spread at home
The game has opened with a projected total of 50 points.
Baltimore Ravens (-3.5) at Los Angeles Chargers (+3.5)
Lamar Jackson’s struggles against the Steelers continued Sunday. The Baltimore Ravens dropped a hard-fought 18-16 road decision to Pittsburgh to fall to 1.5 games back of their division rival in the AFC North.
The Chargers, meanwhile, defeated the Bengals on Sunday Night Football in the penultimate game of the Week 11 ledger. Los Angeles is 7-3 with the victory, still within striking distance of AFC West-leading Kansas City, which suffered its first loss of the season on Sunday at the hands of the Bills.
The Ravens are now an even 3-3 against the spread on the road after failing to cover Sunday.
The over/under line for this game opened at 47.5 points.
