The San Francisco 49ers are looking to get back on track in the NFC West. We cover the 49er’s game odds including the spread, moneyline, and total all down below.
San Francisco 49ers odds
Below, you can find the latest NFL lines for the upcoming 49ers game:
49ers player props
49ers player props for the team’s next matchup appear below. You can use the bet finder tool to search for players and bets for every upcoming NFL game.
San Francisco 49ers odds to win the Super Bowl
Last update: January 2025
When Draftkings, BetMGM, and other popular betting sites released Super Bowl 59 odds in January, the 49ers were at +500. San Francisco’s current odds to win the 2025 Super Bowl are San Francisco 49ers +95455. If you’re not signed up yet, feel free to claim the DraftKings promo code, BetMGM bonus code, Fanatics sportsbook promo, or any other of the best sportsbook promos.
San Francisco 49ers win total odds
San Francisco 49ers futures odds for 2024-25
Here’s a look at the latest 49ers futures odds for the upcoming season. We cover odds to win the NFC, make the playoffs, and more.
| 49ers futures | Current odds |
|---|---|
| Win total | 7.5 (-225) on BetMGM |
| To make the playoffs | Yes +12500 on BetMGM |
| To win the NFC West | San Francisco 49ers +200000 on FanDuel |
| To win the NFC | San Francisco 49ers +50000 on BetRivers |
| To finish in the top two of the NFC West | San Francisco 49ers -10000 on BetMGM |
| To have the best regular season record | San Francisco 49ers +50000 on DraftKings |
California betting resources
Looking for options beyond betting on the 49ers? Below are resources available to California bettors.
Current 49ers sportsbook promotions
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San Francisco 49ers 2024 schedule
| Away team | Home team | Date & time | Location |
|---|---|---|---|
| Jets (+6.5) | 49ers (-6.5) | 9/9, 8:20 p.m. ET | Levi’s Stadium |
| 49ers (-6) | Vikings (+6) | 9/15, 1 p.m. ET | U.S. Bank Stadium |
| 49ers (-2.5) | Rams (+2.5) | 9/22, 4:25 p.m. ET | SoFi Stadium |
| Patriots (+11.5) | 49ers (-11.5) | 9/29, 4:05 p.m. ET | Levi’s Stadium |
| Cardinals (+9.5) | 49ers (-9.5) | 10/6, 4:05 p.m. ET | Levi’s Stadium |
| 49ers (-4) | Seahawks (+4) | 10/10, 8:15 p.m. ET | Lumen Field |
| Chiefs (+2) | 49ers (-2) | 10/20, 4:25 p.m. ET | Levi’s Stadium |
| Cowboys (+4.5) | 49ers (-4.5) | 10/27, 8:20 p.m. ET | Levi’s Stadium |
| 49ers (-4) | Buccaneers (+4) | 11/10, 1 p.m. ET | Raymond James Stadium |
| Seahawks (+9) | 49ers (-9) | 11/17, 4:05 p.m. ET | Levi’s Stadium |
| 49ers (-2.5) | Packers (+2.5) | 11/24, 4:25 p.m. ET | Lambeau Field |
| 49ers (-2) | Bills (+2) | 12/1, 8:20 p.m. ET | Highmark Stadium |
| Bears (+5.5) | 49ers (-5.5) | 12/8, 4:25 p.m. ET | Levi’s Stadium |
| Rams (+6.5) | 49ers (-6.5) | 12/12, 8:15 p.m. ET | Levi’s Stadium |
| 49ers (-1) | Dolphins (+1) | 12/22, 4:25 p.m. ET | Hard Rock Stadium |
| Lions (+4.5) | 49ers (-4.5) | 12/30, 8:15 p.m. ET | Levi’s Stadium |
| 49ers (-5.5) | Cardinals (+5.5) | 1/5, TBD | State Farm Stadium |
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San Francisco 49ers FAQ
San Francisco went 9-11 ATS in the 2023-24 season.
The team released DT Arik Armstead but added other help on the defensive line, including Maliek Collins, Yetur Gross-Matos, and Jordan Elliott.
Brock Purdy returned as QB1 after leading the team to a conference title in his first full season under center for San Francisco.