The San Francisco 49ers are looking to keep their positive momentum in the NFC West. We cover the 49er’s game odds including the spread, moneyline, and total all down below.
San Francisco 49ers postseason odds
Below, you can find the latest NFL lines for the upcoming 49ers game:
49ers player props
49ers player props for the team’s next matchup appear below. You can use the bet finder tool to search for players and bets for every upcoming NFL game.
San Francisco 49ers odds to win the Super Bowl
Last update: June 2026
When Draftkings, BetMGM, and other popular betting sites released Super Bowl 60 odds in January, the 49ers were at +2000. San Francisco’s current odds to win the 2026 Super Bowl are listed below. If you’re not signed up yet, feel free to claim the DraftKings promo code, BetMGM bonus code, Fanatics sportsbook promo, or any other of the best sportsbook promos.
San Francisco 49ers win total odds
California betting resources
Looking for options beyond betting on the 49ers? Below are resources available to California bettors.
Current 49ers sportsbook promotions
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San Francisco 49ers FAQ
Brock Purdy returned as QB1 after leading the team to a conference title in his first full season under center for San Francisco.
The 49ers’ are sitting around +1800 to win, the current odds are slightly better than their preseason odds of +1900, suggesting an improved outlook from oddsmakers following a Week 1 victory over Seattle.