Week 18 NFL Odds: Opening Spreads, Moneylines, & Totals

We’ve reached the final week of the regular season, and there is still final playoff positioning to be decided in each conference.

LSR offers the latest NFL betting odds from top sportsbooks, along with a quick-hitting betting preview for Week 18 games.

NFL Week 18 spreads, moneylines, totals

NFL Week 18 opening odds: spreads, lines, totals

Week 18 NFL odds and analysis 

Cleveland Browns (+17.5) at Baltimore Ravens (-17.5)

Even a Tyler Huntley-led Dolphins team was too much for the Browns to handle in Week 17, with Cleveland failing to score a single TD under Dorian Thompson-Robinson. To make the 20-3 loss worse, Jerome Ford suffered an ankle injury that could well spell the end of his season and make it a D’Onta Foreman-led ground attack for this game, which carries a gargantuan spread that speaks to an almost-certain blowout. 

The Ravens celebrated Christmas Day by dominating the Texans on the road, 31-2. Lamar Jackson became the all-time leader in rushing yards for a QB during the lopsided victory while Derrick Henry put together another dominating performance, setting the Ravens up for the AFC North crown and No. 3 seed with a win in this game.

The Browns are 2-4 ATS as road underdogs this season, while the Ravens sport a 3-3-1 mark against the number as home favorites. Both squads are 2-3 ATS in division games.

The game has opened with an over/under of 42.5 points.

Cincinnati Bengals (-2.5) at Pittsburgh Steelers (+2.5)

The Bengals kept their Hail Mary-esque playoff quest alive Saturday evening with a wild overtime win against the Broncos in which the Joe Burrow-Tee Higgins-Ja’Marr Chase triumvirate was elite. Cincy’s passing game included a 412-yard, three-touchdown tally from Burrow and a combined 20 receptions, 233 yards and three touchdowns (all Higgins) from the two star wideouts. However, Chase Brown did suffer an ankle injury that will bear monitoring throughout the week.

The Steelers lost their third straight game on Christmas Day against the Chiefs, looking mostly inept through the air again despite George Pickens’ return from a hamstring injury. Pittsburgh is still 10-6, but its hopes of capturing the AFC North crown are all but dashed unless the highly unlikely scenario of the Ravens falling to the Browns unfolds in Week 18.

While both teams will be gunning for victories here, the urgency will naturally be heaviest on Cincy’s side, as a win by the Bengals combined with losses by the Broncos and Dolphins, however unlikely those may be, would get Burrow and Co. in.

The Bengals are 5-0 as road favorites this season, while the Steelers are 2-1 as home underdogs. Each team is 3-2 ATS in division clashes.

This game opened with an over/under of 48.5 points.

Carolina Panthers (+7.5) at Atlanta Falcons (-7.5)

The Panthers reverted back to a pumpkin in Week 17, taking a 48-14 walloping from the Buccaneers on the road that included a five-TD day from Baker Mayfield. Bryce Young did hit Adam Thielen for two long scoring passes and continued to show some improvement, and Carolina will have a chance to play spoiler here and head into the offseason with some momentum for Year 2 of the Dave Canales era.

The Falcons saw Michael Penix take another encouraging step in his second start, but Atlanta ultimately fell to the Commanders in OT in Week 17. That left the Falcons’ playoff hopes up in the air, as Tampa Bay is now one game up on them in the NFC South. Therefore, with Raheem Morris’ club holding the head-to-head tiebreaker against the Bucs, they’ll need a win here and a Bucs loss to punch their postseason ticket.

The Panthers are 2-5 ATS as road underdogs this season, while the Falcons have covered on just three of seven occasions as home favorites. Carolina and Atlanta are 2-3 and 3-2, respectively, against the spread in division games.

The game has opened with an over/under of 48.5 points.

Washington Commanders (-3.5) at Dallas Cowboys (+3.5)

The Commanders got to 11 wins in impressive fashion, recording a thrilling overtime win against the Falcons on Sunday night in another installment of a storybook rookie season for Jayden Daniels. Washington is locked into an NFC wild-card spot and appears primed to potentially make some noise in the postseason, even if the depth at wide receiver is a bit suspect behind the current top two of Terry McLaurin and Olamide Zaccheaus. The Commanders will lock up the No. 6 seed with a win in this game, which will give them a more palatable wild-card matchup against the Rams or Buccaneers as opposed to having to travel to Philadelphia as the No. 7 seed.

The Cowboys have no postseason aspirations, but they’ll undoubtedly be looking to both make things more difficult for their division rival and also atone for an ugly 41-7 loss to the Eagles in Week 17. Dallas was playing its first game without CeeDee Lamb (IR-shoulder), and his importance to the offense, which is never really in doubt, was vividly on display by virtue of his absence. Cooper Rush will have one last chance here to enjoy leading the offense in Dak Prescott’s stead.

The Commanders are 1-1 ATS as road favorites this season, while the Cowboys are 1-5 against the number as home underdogs with an NFL-worst ATS +/- of -11.7 points. Meanwhile, Washington and Dallas are 3-2 and 2-3, respectively, against the number in division games.

The game has opened with an over/under of 44.5 points.

Chicago Bears (+9.5) at Green Bay Packers (-9.5)

The Bears’ nightmare continued Thursday night with what may have been considered a low point – a 6-3 loss to the Seahawks at home. Chicago has now dropped 10 straight games and is in real danger of not claiming victory again until 2025, considering the opposition and the fact the Packers have actual incentive despite being locked into a wild-card spot.

Green Bay got down early in Week 17 to Minnesota and couldn’t make up enough ground against the Vikings, falling by a 27-25 score in which Jordan Love may not have been called upon early enough to start slinging the ball. Nevertheless, just like the Commanders, the Pack is fighting to get to the No. 6 seed to avoid the trip to Philadelphia that a No. 7 seed would bring.

The Bears are 1-5-1 ATS as road underdogs this season, and the Packers counter with a 4-2 mark against the spread and ATS +/- of +10.3 points as home favorites. Chicago is 2-2-1 ATS versus NFC North foes, while Green Bay is only 1-4 against the number in division games.

The game has opened with an over/under of 40.5 points.

Houston Texans (+1.5) at Tennessee Titans (-1.5) 

The Texans are in the postseason, but there has to be palpable worry about their ability to do anything but get bounced out of the first round after a 31-2 Christmas Day loss to the Ravens that marked their first game without both Tank Dell (knee) and Stefon Diggs (knee) available. C.J. Stroud and company have had extra time to perform the proverbial autopsy on what went wrong and the Texans did add Diontae Johnson off waivers, which they’ll have to hope helps matters.

The Titans will be going on vacation following this divisional clash, which will mark an end to a tumultuous first year at the helm for Brian Callahan. Mason Rudolph drew the start in Week 17 but was unremarkable in a 20-13 loss to the Jaguars. Callahan will give Will Levis a chance to head into the offseason with some momentum by giving him some playing time in this finale, but the coach also has stated Rudolph will get some snaps.

The Texans are 1-2 ATS as road underdogs this season, and the Titans have posted an 0-4 record against the spread as home favorites. Neither team has fared well against the number in division games – Houston is an NFL-worst 0-4-1 in that split, while Tennessee is 1-4.

The game has opened with an over/under of 37.5 points.

Jacksonville Jaguars (+5.5) at Indianapolis Colts (-5.5)

Mac Jones continued his under-the-radar strong late-season starting stint in Week 17, throwing for a pair of touchdowns without an interception and rushing for 22 yards as well. Brian Thomas Jr. continued his stellar rookie season as well with 91 receiving yards and a TD, and he and Jones could certainly connect plenty in this finale if head coach Doug Pederson takes the reins off with nothing to lose.

The Colts are likely to in either an ornery or defeated mood for this game, as Indy was knocked out of the postseason by falling to the Giants, 45-33, in a big Week 17 upset. The defense allowed Drew Lock to throw for 309 yards and four touchdowns, while also conceding a 171-yard, two-touchdown game to another star rookie wideout, Malik Nabers. Joe Flacco started for Anthony Richardson (back), but the latter could be available for this game.

The game has opened with an over/under of 45.5 points.

Buffalo Bills (-2.5) at New England Patriots (+2.5)

The Bills locked in the No. 2 seed in the AFC without any difficulty in Week 17, running roughshod over the Jets by a 40-14 score. Josh Allen and co. are clicking on all cylinders and are set to take on the wild-card team with the poorest record, and there’s certainly a chance most of the front-line players either sit out or play very limited snaps in this meaningless regular-season finale.

The Patriots took a 40-7 throttling from the Los Angeles Chargers on Saturday afternoon in Week 17 to fall to 3-13. The only reason this spread is this small is because of the expectation of the Bills rolling out a lineup full of reserves on both sides of the ball, as New England doesn’t project to be competitive against any full-strength team based on how it looked versus the Bolts.

The game has opened with an over/under of 38.5 points.

New York Giants (+3) at Philadelphia Eagles (-3)

The Giants’ dark season experienced an extremely rare ray of sunshine in Week 17, as they had the satisfaction of knocking the Colts out of the playoffs with a 45-33 win. Drew Lock’s shocking 309-yard, four-touchdown effort highlighted the afternoon, and Malik Nabers (7-171-2) was a major beneficiary. New York could potentially give Tommy DeVito some playing time in this finale as well.

The Eagles managed a 41-7 rout of the Cowboys without Jalen Hurts (concussion)and sans Kenny Pickett (ribs) for a part of the second half as well. Tanner McKee connected for touchdowns on half of his four passes and almost certainly will get some form of playing time in this matchup, if not an outright start. Head coach Nick Sirianni also noted Wednesday he intends to rest Saquon Barkley, who is just 100 yards away from tying Eric Dickerson’s all-time single-season rushing record of 2,105 yards. 

The game has opened with an over/under of 38.5 points.

New Orleans Saints (+13.5) at Tampa Bay Buccaneers (-13.5)

The Saints rolled with Spencer Rattler again in Week 17 against the Raiders. The rookie had his moments and continued to earn valuable reps but was once again operating with a significantly depleted skill-position group that was missing Alvin Kamara (groin) for the second straight game in addition to all of the other key injuries preceding his.

The Buccaneers looked like a juggernaut at the expense of the Panthers in Week 17, authoring a 48-14 victory that saw Baker Mayfield tie a career high with five touchdown passes, Bucky Irving cross the 1,000-yard mark on the ground for the season, and Mike Evans inch closer to his 11th consecutive 1,000-yard campaign. Tampa Bay also kept itself in play for the NFC South title irrespective of whether the Falcons win against the Commanders on Sunday night, leaving this game as another must-win scenario.

This game opened with an over/under of 43.5 points.

Kansas City Chiefs (+8.5) at Denver Broncos (-8.5)

The Chiefs have wrapped up the AFC’s No. 1 seed and a first-round bye, which gives them some priceless downtime with which to get the likes of Patrick Mahomes and Chris Jones fully healthy for the final leg of their three-peat quest. That means we’ll be treated to a Carson Wentz-led offense full of second- and third-stringers in a matchup that has plenty of importance for Kansas City’s opponent.

The Broncos narrowly missed out on clinching their first playoff spot since 2015 for the second week in a row Saturday against the Bengals in an overtime loss. However, Bo Nix once again showed that he’s ready to take on all comers with an impressive performance, and Denver still has a favorable scenario in front of it for this regular-season finale that will allow it to play a Chiefs team that will be resting its top players. If the Broncos take care of business as is likely, they’ll punch their postseason ticket in Nix’s first season.

This game opened with an over/under of 39.5 points.

Los Angeles Chargers (-5.5) at Las Vegas Raiders (+5.5)

The Chargers continued the march to the postseason with a 40-7 win over the Patriots that marked the return of J.K. Dobbins from injured reserve. Justin Herbert and Ladd McConkey spearheaded the offensive effort and set Los Angeles up to secure the fifth seed with a victory in this game and a Steelers loss to the Bengals. A win and Pittsburgh win or a Chargers loss makes them the No. 6 seed and sets up a matchup versus the Steelers and Ravens.

The Raiders have gotten to 4-12 with back-to-back wins but may not be able to save Antonio Pierce’s job. Aidan O’Connell, Brock Bowers, Tre Tucker and Ameer Abdullah are among the feel-good stories down the stretch for the Silver and Black, but given the Chargers have some incentive here and Vegas’ two recent wins have come against the Jaguars and Saints, this game could very well end badly for the Raiders.

The game has opened with an over/under of 41.5 points.

Seattle Seahawks (+1.5) at Los Angeles Rams (-1.5)

The Seahawks moved to 9-7 with an ugly 6-3 win over the Bears on Thursday Night Football, which kept them within a game of the Rams and alive for a playoff berth for a few days despite Los Angeles’ subsequent victory over the Cardinals on Saturday night. However, the Commanders’ win over the Falcons on Sunday night eliminated Seattle from playoff contention. Kenneth Walker is on injured reserve with an ankle injury, which leaves Zach Charbonnet and Kenny McIntosh in charge of the ground attack for this Week 18 finale.

The Rams continued their late-season surge with a 13-9 victory over the Cardinals on Saturday night that they needed a last-second acrobatic end-zone interception to salvage. Los Angeles has prevailed in five straight to reach 10-6 and has now clinched the NFC West thanks to the Commanders’ win over the Falcons.

This game opened with an over/under of 41.5 points.

Miami Dolphins (-1.5) at New York Jets (+1.5)

The Dolphins pulled off a 20-3 road victory against the Browns in Week 17 with Tyler Huntley quarterbacking in place of Tua Tagovailoa (hip), keeping themselves in the playoff hunt in the process. Another Miami win paired with a Broncos loss to the Chiefs gets the Fins in as a wild card, albeit with an unenviable trip to Buffalo as their reward.

The Jets will close out an ugly season in this game, but there are still a couple of incentives on the table. Aaron Rodgers will be aiming for career touchdown pass No. 500 in what could be his final game as a Jet, and perhaps his career. New York could also play a big spoiler role here against their division rival, although based on how the Jets looked against the Bills in Week 17, the motivation level is in question.

The game has opened with an over/under of 40.5 points.

San Francisco 49ers (-1.5) at Arizona Cardinals (+1.5)

The Niners’ 40-34 loss to the Lions on Monday night saddled with San Francisco with double-digit losses since 2020. Brock Purdy also sustained a bruised elbow in the game, an injury that will keep him out of Week 18 and afford Joshua Dobbs, who recorded a rushing TD late in Purdy’s stead against Detroit, a spot start in this finale.

The Cardinals are also eliminated from playoff contention, so we could be treated to a wild, no-holds-barred battle between two division rivals that have nothing to lose. Arizona suffered another close loss to the Rams in Week 17, although Trey McBride finally recorded his first TD catch of ‘24. James Conner sustained a knee injury that could put an end to a fine season that’s seen him amass a career-high 1,094 rushing yards.

The game has opened with an over/under of 46.5 points.

Minnesota Vikings (+2.5) at Detroit Lions (-2.5)

The Vikings held off the Packers after building a big lead in Week 17, escaping with a 27-25 home victory that was their ninth straight. That set up this showdown for the NFC North and the conference’s No. 1 seed, one where the Vikes will also be looking to avenge a 31-29 loss from Week 7. Sam Darnold continued to impress, throwing for 377 yards and three touchdowns in Week 17.

The Detroit Lions will play Monday night in San Francisco, and the outcome of that game, which Detroit is favored in, won’t change the stakes of this one. Dan Campbell’s squad will head into the road matchup against Kyle Shanahan’s depleted crew with a perfect 7-0 mark on the road and victories in 12 of its last 13 games overall.

This game opened with an over/under of 52.5 points.