College football odds are taking center stage in Week 11 as the playoff landscape takes shape.
Primetime matchups between top-ranked teams in Georgia vs. Ole Miss and Alabama vs. LSU headline this week’s most-bet games. Beyond the SEC, two Big Ten clashes in Penn State vs. Washington and Michigan vs. Indiana could have significant ramifications on college football odds and playoff seeding, while Colorado vs. Texas Tech could have significant Heisman implications as the season reaches its critical final stretch.
Below, we dive into each of these highly bet games, where the money is going and how each team matches up.
| Matchup | Opening Spread | Opening Moneyline | Opening Total |
|---|---|---|---|
| Georgia vs. Ole Miss | Georgia -3.5 | Georgia -225/Ole Miss +180 | 54.5 |
| Alabama vs. LSU | Alabama -2.5 | Alabama -125/LSU +105 | 57.5 |
| Michigan vs. Indiana | Indiana -12.5 | Indiana -650/Michigan +475 | 49.5 |
| Colorado vs. Texas Tech | Colorado -2.5 | Colorado -155/Texas Tech +125 | 62.5 |
| Penn State vs. Washington | Penn State -13.5 | Penn State -650/Washington +450 | 46.5 |
Georgia vs. Ole Miss
- Opening spread: Georgia -3.5
- Opening moneyline: Georgia -225/Ole Miss +180
- Opening total: 54.5
No. 3 Georgia (7-1 straight up, 2-6 against the spread) vs. No. 16 Ole Miss (7-2 SU, 6-3 ATS) is this week’s marquee college football matchup, drawing substantial betting interest at BetMGM.
The line opened at Georgia -3.5 but has since shifted to -3, with the Bulldogs pulling in 78% of bets and 76% of spread handle at BetMGM. The total has also moved slightly, from 54.5 to 55.5, with 59% of bets and 69% of handle on the over.
For Georgia, every November game is a virtual playoff, as one more loss would all but end the Bulldogs’ title hopes. Head coach Kirby Smart’s team dominated Florida in its last outing, relying heavily on a punishing ground game. But quarterback Carson Beck has struggled lately with eight interceptions in his last three games. Ole Miss faces a tough road to the playoff, with a win over Georgia being essential to stay in the hunt. On the injury front, the Rebels could be buoyed by the possible return of standout wide receiver Jordan Watkins, upgraded to questionable, though center Reece McIntyre will likely be absent.
The Bulldogs, holding steady as a narrow favorite, will aim to replicate last year’s 52-17 blowout over Ole Miss. With Georgia’s ground attack paired against a resilient Ole Miss defense, this clash has all the makings of a tightly contested SEC showdown, crucial for both teams’ playoff aspirations.
Alabama vs. LSU
- Opening spread: Alabama -2.5
- Opening moneyline: Alabama -125/LSU +105
- Opening total: 57.5
No. 11 Alabama (6-2 SU/4-4 ATS) vs. No. 15 LSU (6-2/3-5 ATS) should be another intense SEC battle, with Alabama now a three-point favorite, moving slightly from the -2.5 opening line.
LSU is drawing 66% of spread bets and 70% of handle at BetMGM. The total has also nudged up from 57.5 to 58.5, with a slight public lean toward the over.
Alabama’s defense has shown flashes of dominance but has also struggled at times with penalties and extending drives. Despite a solid showing against Missouri, the Tide have allowed big plays against other SEC teams and failed to capitalize on defensive stops, especially in their one loss to Vanderbilt.
LSU will lean on quarterback Garrett Nussmeier, who is first in the conference in completions and second in passing yards. An inconsistent Tigers defense will look to pressure Alabama by capitalizing on any defensive lapses. Head coach Brian Kelly is aiming to overcome Alabama’s dominance in this series and hand the team its second loss in the post-Nick Saban era.
Michigan vs. Indiana
- Opening spread: Indiana -12.5
- Opening moneyline: Indiana -650/Michigan +475
- Opening total: 49.5
No. 8 Indiana (9-0 SU, 8-1 ATS) hosts Michigan (5-4 SU, 2-7 ATS) in a Big Ten clash that has seen the undefeated Hoosiers move from -12.5 to –14.5
Indiana has drawn 59% of bets and 68% of handle on the spread at BetMGM, while the total has held at 49.5, even as 83% of bets and 82% of the money pours in on the over.
The Hoosiers, eyeing a potential playoff berth, have found their stride with a balanced attack and a defense ranked No. 2 against the run. With a bye before facing Ohio State, Indiana should be holding nothing back against a Michigan team that has dominated the Hoosiers in recent history.
Michigan is coming off a 38-17 loss to top-ranked Oregon and has shown flashes of offensive potential with quarterback Davis Warren despite some late-game struggles. Michigan’s rushing attack has added variety, but it’ll need to minimize defensive breakdowns to stay competitive against Indiana’s balanced offense.
Colorado vs. Texas Tech
- Opening spread: Colorado -2.5
- Opening moneyline: Colorado -155/Texas Tech +125
- Opening total: 62.5
No. 20 Colorado (6-2 SU/6-2 ATS)heads south to face Texas Tech (6-3 SU/5-3-1 ATS) in a high-stakes Big 12 matchup. Colorado opened as a 2.5-point favorite, but the line has since shifted to -4.5.
At BetMGM, 60% of spread bets and 64% of handle is on Colorado, while the total remains at 62.5 despite a whopping 88% of bets and 87% of handle on the over.
Colorado’s passing game, led by quarterback Shedeur Sanders, ranks No. 8 in the country and has carried the Buffaloes into the Big 12 title hunt. Coming off a bye week following a win over Cincinnati, Sanders will look to keep hitting star receiver and Heisman favorite Travis Hunter, who had nine catches for 153 yards and two touchdowns in his last outing. With a possible shot at the College Football Playoff on the line, Coach Prime and Co. will have plenty to play for in this conference matchup.
Texas Tech, meanwhile, is riding the high of an upset victory over then-No. 11 Iowa State. Quarterback Behren Morton and receiver Josh Kelly have been standout performers, with Kelly hauling in 127 yards and a touchdown last game. However, the Red Raiders face potential setbacks with six starters questionable due to injuries.
With Texas Tech’s defense allowing 35 or more points in three of its last five games and Colorado proving efficient both at home and on the road, this contest has all the makings of an offensive shootout, which is why it is one of the highest game totals of the week at sportsbooks.
Penn State vs. Washington
- Opening spread: Penn State -13.5
- Opening moneyline: Penn State -650/Washington +450
- Opening total: 46.5
No. 6 Penn State (7-1 SU/3-5 ATS) faces a critical matchup against Washington (5-4 SU/4-5 ATS) in Happy Valley, with playoff implications on the line after their tough loss to Ohio State.
This opened at Penn State -13.5 and has not moved despite the Nittany Lions drawing 81% of bets and 82% of handle at BetMGM. The total has moved from 45.5 to 46.5, with the under drawing just 31% of bets but 56% of handle.
The Nittany Lions will lean on their dominant rushing attack to exploit Washington’s 92nd-ranked rush defense. Although their offense has been methodical, they need to establish a rhythm and control the clock to avoid getting into a shootout, where Penn State has struggled finding explosive plays.
Washington, on the other hand, is in a far less desperate situation; its goal will be to play spoiler rather than secure a playoff spot. However, the team’s road struggles could make this a tough test, especially after back-to-back away losses and an exhausting game against USC. With the Huskies’ elite pass defense facing a Penn State offense that is less potent through the air, they’ll have to stop the run to stay competitive.
