The Arizona Cardinals are underdogs on the road in Week 4 against the San Francisco 49ers. The Cardinals are coming off their first win of the season in a shocking upset at home against the Cowboys on Sunday, but are still underdogs against the unbeaten 49ers, who come into this game as heavy favorites, with moneyline odds of .
Arizona is off to a 1-2 start after securing the biggest upset of the week, defeating the previously unbeaten Cowboys at home in Week 3. The Cardinals are at the bottom of the league in odds to win Super Bowl 58 at +50000. Here’s a closer look at the latest Cardinals betting lines, futures, and props.
Arizona Cardinals odds: Spread, moneyline, and over/under
Below are the latest lines for the next Cardinals game. If a bet interests you, click on the odds to go directly to the sportsbook.
Week 4 odds: Cardinals hit the road as big underdogs against 49ers
The Arizona Cardinals showed that their big first-half lead against the Giants in Week 2 was no fluke as they did the same thing at home against the undefeated Cowboys in Week 3 — and this time Arizona never relinquished the lead, winning 28-16. That improved the Cardinals to 1-2 on the season, as QB Joshua Dobbs threw for 189 yards and one TD and RB James Conner ran for 98 yards on 14 carries. LB Josh Woods suffered an ankle injury and is questionable for Sunday’s game.
The San Francisco 49ers are off to a 3-0 start after beating the Giants at home last week on Thursday Night Football. The 49ers are now the favorite to win Super Bowl 58 and are third-best in the league in both points scored per game and points allowed. RB Christian McCaffrey has scored in every game so far, but WR Brandon Aiyuk went down with a shoulder injury and is questionable for Week 4.
- Point spread: Cardinals , 49ers
- Moneyline: Cardinals , 49ers
- Total: Over/under
The Cardinals were 4-13 on the moneyline, 8-9 against the spread, and 8-7-2 on the over/under last season. The 49ers went 15-5 against the spread and 10-10 on the over/under.
Cardinals vs. 49ers player props
Last season, the Cardinals averaged 20 points per game and allowed 26.4. Arizona was the fourth-worst team in the league in turnovers, coughing up the ball 25 times last season. James Conner leads the team this season with 266 rushing yards through three games so far, averaging 5.2 yards per carry. The 49ers have one of the league’s top-scoring offenses and best defenses. RB Christian McCaffrey is averaging 117.7 rushing yards per game, with a touchdown in each game so far. Here are some of the top Cardinals vs. 49ers player props. Use the tab to switch between categories.
Daily Deals in Virginia
Cardinals odds to win the Super Bowl
Last updated: October 2023
Sportsbooks released futures odds for the 2024 Super Bowl in January 2023. At that point, the Cardinals were at +20000, tied for last place on the board with the Texans. The Cardinals’ current odds to win Super Bowl 58 stand at . Arizona last made it to the postseason in 2021, losing to the Rams in the wild card round. The franchise has advanced to the big game just once, losing to the Steelers at Super Bowl XLIII.
Arizona Cardinals futures odds for 2023-24
In addition to betting on the winner of the next Super Bowl, you can place a number of other NFL futures bets. Here are the latest Cardinals futures odds in other key markets.
- To win the NFC:
- To win the NFC West:
- Regular season win total:
- Kyler Murray MVP odds:
2023 Cardinals Player Stats
Last Updated on 09.27.2023| Player | GP Games Played | CMP% Completion Percentage | YDS Passing Yards | YDS/G Yards Per Game | YDS/C Yards Per Completion | TDS Passing Touchdowns | INT Interceptions thrown | RTG Passer Rating |
|---|---|---|---|---|---|---|---|---|
| Joshua Dobbs – QB | 3 | 72.0% | 549 | 183.0 | 9.3 | 2 | 0 | 67.2 |
| Clayton Tune – QB | 1 | 0.0% | 0 | 0.0 | 0.0 | 0 | 0 | 0.0 |
| Kyler Murray – QB | 0 | 0.0% | 0 | 0.0 | 0.0 | 0 | 0 | 0.0 |
| Jeff Driskel – QB | 0 | 0.0% | 0 | 0.0 | 0.0 | 0 | 0 | 0.0 |
| Player | GP Games Played | ATT Rushing Attempts | YDS Rushing Yards | YDS/C Yards Per Carry | YDS/G Rushing Yards Per Game | TDS Rushing Touchdowns |
|---|---|---|---|---|---|---|
| James Conner – RB | 3 | 51 | 266 | 5.2 | 88.7 | 2 |
| Joshua Dobbs – QB | 3 | 12 | 93 | 7.8 | 31.0 | 1 |
| Rondale Moore – WR | 3 | 5 | 66 | 13.2 | 22.0 | 1 |
| Marquise Brown – WR | 3 | 1 | 29 | 29.0 | 9.7 | 0 |
| Keaontay Ingram – RB | 3 | 12 | 15 | 1.3 | 5.0 | 0 |
| Player | GP Games Played | TGTS Targets | REC Receptions | YDS Receiving Yards | CTP% Catch Percentage | YDS/R Yards Per Reception | YAC/G Yards After Catch Per Game | TDS Receiving Touchdowns |
|---|---|---|---|---|---|---|---|---|
| Michael Wilson – WR | 3 | 9 | 7 | 161 | 77.8% | 23.0 | 18.0 | 0 |
| Marquise Brown – WR | 3 | 22 | 14 | 143 | 63.6% | 10.2 | 7.0 | 2 |
| Zach Ertz – TE | 3 | 20 | 14 | 83 | 70.0% | 5.9 | 10.7 | 0 |
| Trey McBride – TE | 3 | 6 | 5 | 57 | 83.3% | 11.4 | 7.3 | 0 |
| Rondale Moore – WR | 3 | 10 | 8 | 55 | 80.0% | 6.9 | 14.7 | 0 |
| James Conner – RB | 3 | 8 | 7 | 26 | 87.5% | 3.7 | 11.7 | 0 |
| Zach Pascal – WR | 3 | 2 | 1 | 9 | 50.0% | 9.0 | 4.0 | 0 |
| Keaontay Ingram – RB | 3 | 1 | 1 | 8 | 100.0% | 8.0 | 4.3 | 0 |
| Greg Dortch – WR | 3 | 0 | 0 | 0 | 0.0% | 0.0 | 0.0 | 0 |
| Geoff Swaim – TE | 3 | 0 | 0 | 0 | 0.0% | 0.0 | 0.0 | 0 |
| Player | GP Games Played | INT Interceptions | PD Passes Defended | FF Fumbles Forced | FR Fumbles Recovered | SACK QB Sacks | TOT Total Tackles | SOLO Solo Tackles | AST Assisted Tackles |
|---|---|---|---|---|---|---|---|---|---|
| Dennis Gardeck – OLB | 3 | 0 | 0 | 1 | 0 | 3 | 10 | 9 | 1 |
| Victor Dimukeje – OLB | 3 | 0 | 0 | 1 | 0 | 3 | 7 | 5 | 2 |
| Zaven Collins – OLB | 3 | 1 | 0 | 0 | 1 | 2 | 7 | 4 | 3 |
| Kyzir White – ILB | 3 | 1 | 0 | 0 | 0 | 1 | 30 | 18 | 12 |
| Carlos Watkins – DT | 2 | 0 | 0 | 0 | 0 | 1 | 7 | 4 | 3 |
| Leki Fotu – DT | 2 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 1 |
| Jonathan Ledbetter – DL | 3 | 0 | 0 | 0 | 0 | 1 | 12 | 8 | 4 |
| Marco Wilson – CB | 3 | 0 | 0 | 0 | 0 | 0 | 14 | 12 | 2 |
| Budda Baker – S | 1 | 0 | 0 | 0 | 0 | 0 | 5 | 3 | 2 |
| Josh Woods – ILB | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2 |
| Tyreek Maddox-Williams – LB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Christian Matthew – CB | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Myjai Sanders – OLB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cameron Thomas – OLB | 3 | 0 | 0 | 0 | 1 | 0 | 4 | 3 | 1 |
| K’Von Wallace – S | 3 | 0 | 0 | 0 | 0 | 0 | 22 | 12 | 10 |
| Jalen Thompson – S | 3 | 1 | 0 | 0 | 0 | 0 | 20 | 13 | 7 |
| Kevin Strong – DL | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Kris Boyd – CB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L.J. Collier – DL | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 |
| Rashad Fenton – CB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Ezekiel Turner – ILB | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
| Davion Taylor – LB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Roy Lopez – DT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| BJ Ojulari – OLB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Jesse Luketa – OLB | 3 | 0 | 0 | 0 | 0 | 0 | 4 | 3 | 1 |
| Kei’Trel Clark – CB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Joey Blount – FS | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dante Stills – DT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Ben Stille – DE | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Jacob Slade – DT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Qwuantrezz Knight – S | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Andre Chachere – S | 1 | 0 | 0 | 0 | 0 | 0 | 4 | 3 | 1 |
| Garrett Williams – CB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Bobby Price – CB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Owen Pappoe – ILB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Krys Barnes – ILB | 3 | 0 | 0 | 0 | 0 | 0 | 16 | 13 | 3 |
| Starling Thomas V – CB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Eric Banks – DL | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Divaad Wilson – CB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Antonio Hamilton Sr. – CB | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Arizona Cardinals Injuries
| Player | Pos Position | Injury | Status | Snaps/g Snaps Per Game | Comment |
|---|---|---|---|---|---|
| Rashad Fenton | CB | Undisclosed | Out | 0 | Fenton is dealing with an undisclosed injury and has been placed on the injured reserve list. He will miss the 2023-24 season. |
| Pat Elflein | OL | Hip | Out | 0 | Elflein is dealing with a hip injury and has been placed on the injured reserve list. He will miss the 2023-24 season. |
| Paris Johnson Jr. | OL | Ankle | Questionable | 0 | Johnson Jr was limited in practice on Friday heading into Week 4 versus the 49ers. |
| Myjai Sanders | OLB | Hand | Out | 0 | Sanders is dealing with a hand injury and has been placed on the injured reserve list. He will miss at least four games. |
| Matt Hembrough | LS | Back | Out | 0 | Hembrough is dealing with a back injury and has been placed on the injured reserve list. He will miss the 2023-24 season. |
| Marquise Brown | WR | Thumb | Questionable | 56.7 | Brown was limited in practice on Friday heading into Week 4 versus the 49ers. |
| Marlon Mack | RB | Achilles | Out | 0 | Mack suffered a torn Achilles and has been placed on the injured reserve list. He will miss the 2023-24 season. |
| L.J. Collier | DL | Bicep | Out | 0 | Collier is dealing with a bicep injury and has been placed on the injured reserve list. He will miss at least four games. |
| Kyler Murray | QB | Knee | Out | 0 | Murray is recovering from a torn ACL and has been placed on the physically unable to perform list. He will miss at least four games. |
| Krys Barnes | ILB | Finger | Questionable | 0 | Barnes was limited in practice on Friday heading into Week 4 versus the 49ers. |
| Keaontay Ingram | RB | Neck | Questionable | 8 | Ingram did not practice on Friday heading into Week 4 versus the 49ers. |
| Josh Woods | ILB | Ankle | Out | 0 | Woods has been ruled out heading into Week 4 versus the 49ers. |
| Jonathan Ledbetter | DL | Finger | Out | 0 | Ledbetter has been ruled out heading into Week 4 versus the 49ers. |
| Jon Gaines II | OL | Knee | Out | 0 | Gaines is dealing with a knee and has been placed on the injured reserve list. He will miss the 2023-2024 season. |
| Hayden Howerton | G | Undisclosed | Out | 0 | Howerton, a practice squad player, is dealing with an undisclosed injury and has been placed on the injured reserve list. |
| Garrett Williams | CB | Knee | Out | 0 | Williams is dealing with a knee injury and has been placed on the non-football injury list. He will miss at least four games. |
| Dennis Daley | OL | Ankle | Out | 0 | Daley is dealing with an ankle injury and has been placed on the injured reserve list. He will miss at least four games. |
| Carlos Watkins | DT | Bicep | Out | 0 | Watkins suffered a biceps injury and has been placed on the injured reserve list. He will miss at least four games. |
| Budda Baker | S | Hamstring | Out | 0 | Baker is dealing with a hamstring injury and has been placed on the injured reserve list. He will miss at least four games. |
Cardinals 2023-24 schedule
Upcoming games
Cardinals news and updates
The Cardinals made sweeping changes this offseason following a disappointing campaign. Monti Ossenfort, most recently the player personnel director for the Titans, is the new GM, while former Eagles defensive coordinator Jonathan Gannon is the head coach. In late May, the club released wide receiver DeAndre Hopkins. Kyler Murray is on the physically unable-to-perform list as he continues to rehab from an ACL injury. Arizona pulled off a major upset in Week 3, beating the Cowboys at home to get their first win of the season, improving to 1-2.
Arizona Cardinals draft picks
The Cardinals originally had the third overall pick in the 2023 NFL draft. The team made a pair of trades after the draft opened and wound up in the sixth slot. The club’s selection was OT Paris Johnson Jr. out of Ohio State, a highly regarded player who could turn into a building block for a franchise that has its sights set on the future.
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Arizona Cardinals FAQ
Are the Cardinals Super Bowl contenders?
Sportsbooks do not view Arizona as a legitimate contender to win Super Bowl 58. After the winless start in the first two weeks, the Cardinals dropped into sole possession of last place in Super Bowl odds.
How did the Cardinals do against the spread last season?
The Cardinals went 8-9 against the spread a season ago and 4-13 on the moneyline. As for totals, the club checked in with a final mark of 8-7-2.
Whom did the Cardinals add and lose in the offseason?
During the early stages of free agency, the Cardinals signed LB Kyzir White, formerly of the Eagles. Departures included DE Zach Allen, who inked a deal with the Broncos, and CB Byron Murphy, who signed with the Vikings. At the NFL draft, the team’s first-round pick was OT Paris Johnson Jr.
Is Kyler Murray staying in Arizona?
Kyler Murray signed a five-year, $230.5 million contract extension with the Cardinals during the 2022 offseason. The deal runs through 2028. Murray closed out last season on injured reserve with a knee injury. He’s on the PUP list to begin this season and will miss at least the first four games.