NFL Preview: Broncos vs. Bills Odds, Player Props, Betting Lines & Injury Report 


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Slumping Bills looking to bounce back against refreshed Broncos

Over their last five games, the Buffalo Bills are 2-3. Their two wins were a 14-9 victory over the New York Giants at home and a 24-18 win, also at home, against the Tampa Bay Buccaneers. They lost on the road in Week 9 to the Cincinnati Bengals. Quarterback Josh Allen threw for 258 yards, one touchdown, and one interception.

As for the Denver Broncos, they’re coming off a bye and will be on the road against the Bills. Before the bye, the Broncos had wins over the Green Bay Packers and Kansas City Chiefs. In Denver’s Week 8 win over the Chiefs, Russell Wilson threw for three touchdowns on 114 yards passing. Both teams now look forward to Week 10 of the season, as they square off on Monday Night Football.

Bills will face a struggling Broncos defense

Per game this season, the Broncos have allowed 28.3 points, 251.8 passing yards, and 154.1 rushing yards. They’re at the bottom of the NFL in both total yards allowed per game and points per game this season. Allen, meanwhile, is completing 71.3% of his passes for 2,423 yards, 18 touchdowns, and nine interceptions so far this season. 

For Broncos, creating turnovers could be key against Bills

The Broncos are averaging 2.3 takeaways per game over their last three, and here, they’ll face a Bills offense with a 2.8% interception rate through Week 9. Allen has thrown an interception in all but two games this season.

Broncos vs. Bills odds and betting lines

Broncos vs. Bills player props

Below is a player prop tool that will allow you to select any player or team to see all their listed prop odds. Simply search for the player or team you desire.

Broncos vs. Bills head to head

STATS
Broncos logo Broncos DEN
Bills logo Bills BUF
Offense Ranking OFF RNK28th22nd
Defense Ranking DEF RNK3rd21st
Offense Net Yards Per Game OFF NET YPG270.6299.8
Defense Net Yards Per Game DEF NET YPG271.2342.4
Passing Yards Per Game PASS YPG163.8181.6
Turnovers Committed Per Game TOC PG1.40.4

Broncos vs. Bills injury report: Who’s out, who’s starting 

Heading into Week 10, the Broncos have no new injury reports coming off a bye. Brandon Johnson went on injured reserve on Oct. 28. The Bills went into Week 9 against the Cincinnati Bengals without several players, and Terrel Bernard left Week 9 with a concussion. 

Bills Week 10 injury update: Bernard leaves Week 9, now questionable

Player Injury Status
Baylon SpectorHamstringQuestionable 
A.J. KleinBackQuestionable
Terrel BernardConcussionQuestionable

Broncos Week 10 injury update: Jackson remains suspended

Player Pos Position Injury Status Snaps/g Snaps Per Game Comment
Alex Palczewski OT Ankle Questionable 36.5 Week 6
Alex Singleton ILB Torn ACL Out 66 Singleton has suffered a torn ACL and has been placed on the injured reserve list. He will miss the rest of the 2024-25 season.
Audric Estime RB Ankle Out 12 Estime is dealing with an ankle injury and has been placed on the injured reserve list. He will miss at least four games.
Baron Browning OLB Foot Out 29 Browning is dealing with a foot injury and has been placed on the injured reserve list. He will miss at least four games.
Damarri Mathis CB Ankle Out 0 Mathis is dealing with a high ankle sprain and has been placed on the injured reserve list. He will miss at least four games.
Delarrin Turner-Yell S Knee Out 0 Turner-Yell is recovering from a torn ACL and has been placed on the physically unable to perform list. He will miss at least four games.
Devaughn Vele WR Gameday Inactive Out 34 Week 5
Drew Sanders ILB Achilles Out 0 Sanders is recovering from a torn Achilles and has been placed on the physically unable to perform list. He will miss at least four games.
Eyioma Uwazurike DL Gameday Inactive Out 0 Week 5
Greg Dulcich TE Gameday Inactive Out 30 Week 5
Kris Abrams-Draine CB Gameday Inactive Out 0 Week 5
Luke Wattenberg C Ankle Questionable 52 Week 6
Mike McGlinchey OT Knee Out 66.5 McGlinchey is dealing with a MCL sprain and has been placed on the injured reserve list. He will miss at least the next four games.
Quinn Bailey OT Ankle Out 0 Bailey suffered a fractured right ankle and has been placed on the injured reserve list. He will miss the 2024-25 season.
Tyler Badie RB Back Out 7 Badie is dealing with a back injury and has been placed on the injured reserve list. He will miss at least four games.
Zach Wilson QB Gameday Inactive Out 0 Week 5