Preseason Week 2 Odds: NFL Spreads, Moneylines And Totals

Written By Christopher Feery on August 19, 2022 - Last Updated on August 22, 2022

The first week of the NFL preseason is in the books. The next slate of games gets underway this Thursday, Aug. 19.

All 32 teams will take the field over the course of five days. The action wraps up with an exhibition edition of Monday Night Football.

You can bet on preseason games at legal online sportsbooks, but wagering options are limited compared to the regular season. Here’s a look at NFL Preseason Week 2 odds and what you can bet on this week.

NFL Preseason Week 2 betting odds

NFL Preseason Week 2 schedule

The Week 2 schedule is spread out over five days. The slate begins with a standalone game Thursday and wraps up with a single contest Monday. In between, it is a busy Friday through Sunday window with 14 games in total. Here’s a look at all 16 matchups.

Preseason game odds last updated: October 7, 2022

Chicago Bears vs. Seattle Seahawks best odds

  • When: Thursday, Aug. 18, 8 p.m. ET
  • Watch: ESPN
  • Moneyline: Bears , Seahawks
  • Spread: Bears , Seahawks
  • Total:

The Bears opened the preseason with a 19-14 win over the Chiefs. Justin Fields saw limited time in the game, but we could get a more extended look at him and the rest of the offense this time around. The Seahawks lost to the Steelers by a score of 32-25 with Drew Lock and Geno Smith splitting snaps. The training camp battle between the two QBs continues.

Carolina Panthers vs. New England Patriots best odds

  • When: Fri., Aug. 19, 7 p.m. ET
  • Watch: NFL Network
  • Moneyline: Panthers , Patriots
  • Spread: Panthers , Patriots
  • Total:

The Panthers picked up a 23-21 win over the Commanders last week. Baker Mayfield and Sam Darnold both made brief appearances, but they should get more time for this one as they look to settle the QB competition. The Patriots lost a 23-21 decision to the Giants and left Mac Jones on the sidelines. The second-year QB could be more involved for this tilt.

New Orleans Saints vs. Green Bay Packers best odds

  • When: Fri., Aug. 19, 8 p.m. ET
  • Moneyline: Saints , Packers
  • Spread: Saints , Packers
  • Total:

These two NFC playoff hopefuls both came up short last week. The Saints lost a close one to the Texans, while the Packers fell by seven points to the 49ers. Jordan Love saw the bulk of the snaps for Green Bay, and it’ll likely be more of the same this week. Jameis Winston didn’t see time against Houston, but we’ll probably see more out of the first unit this week.

Houston Texans vs. Los Angeles Rams best odds

  • When: Fri., Aug. 19, 10 p.m. ET
  • Watch: NFL Network
  • Moneyline: Texans , Rams
  • Spread: Texans , Rams
  • Total:

The Texans and Rams both notched victories last week over the Saints and Chargers, respectively. Houston is getting set for what could be a trying season, as the team’s win total is set at 4.5. The defending champion Rams are among the top favorites in Super Bowl futures, but playing time for starters could be on the light side throughout the preseason.

Denver Broncos vs. Buffalo Bills best odds

  • When: Sat., Aug. 20, 1 p.m. ET
  • Watch: NFL Network
  • Moneyline: Broncos , Bills
  • Spread: Broncos , Bills
  • Total:

During the regular season, this would be a must-see matchup of two AFC favorites. For the preseason, we shouldn’t expect to see Russell Wilson and Josh Allen dueling it out for the entirety of the game. Denver picked up a 17-7 win over the Cowboys last week, while the Bills handled the Colts by a final score of 27-24.

Detroit Lions vs. Indianapolis Colts best odds

  • When: Sat., Aug. 20, 1 p.m. ET
  • Moneyline: Lions , Colts
  • Spread: Lions ,
  • Total:

As this ‘year’s ‘Hard Knocks’ team on HBO, the Lions are receiving a good deal of preseason attention. They came up short in their first exhibition game with a 27-23 home loss to the Falcons. The Colts’ first-team offense saw some time in the loss to the Bills, but it wasn’t smooth sailing. We’ll see if Matt Ryan and company work out the kinks this time around.

Washington Commanders vs. Kansas City Chiefs best odds

  • When: Sat., Aug. 20, 4 p.m. ET
  • Watch: NFL Network
  • Moneyline: Commanders , Chiefs
  • Spread: Commanders , Chiefs
  • Total:

The Commanders lost a close one at home to the Panthers, while the Chiefs went scoreless in the second half of a five-point defeat to the Bears. Patrick Mahomes led a scoring drive on Kansas City’s first series, and Carson Wentz was in for several snaps for Washington. The listed total is one of the highest on the board for preseason Week 2.

Tampa Bay Buccaneers vs. Tennessee Titans best odds

  • When: Sat., Aug. 20, 7 p.m. ET
  • Watch: NFL Network
  • Moneyline: Buccaneers , Titans
  • Spread: Bucs , Titans
  • Total:

Tom Brady has been away from camp in Tampa Bay but should be returning soon. If he’s at the game, it’ll likely be in a spectator role. The Buccaneers lost a two-point decision to the Dolphins last week, while the Titans were walloped by the Ravens. Tennessee could step things up for what could be the dress rehearsal game for Week 1 of the regular season.

Las Vegas Raiders vs. Miami Dolphins best odds

  • When: Sat., Aug. 20, 7 p.m. ET
  • Moneyline: Raiders , Dolphins
  • Spread: Raiders , Dolphins
  • Total:

The Raiders are undefeated in the preseason. They took down the Jaguars in the Hall of Fame Game and followed that up with a 26-20 win over the Vikings on Sunday. For the Dolphins, Skylar Thompson handled all of the snaps behind center in the victory over Tampa Bay. Tua Tagovailoa and company will probably see some time in this contest.

San Francisco 49ers vs. Minnesota Vikings best odds

  • When: Sat., Aug. 20, 7 p.m. ET
  • Moneyline: 49ers , Vikings
  • Spread: 49ers , Vikings
  • Total:

The 49ers hit the road for preseason Week 2 after picking up a 28-21 home win over the Packers. The Vikings lost by six at home to the Raiders, but it was backups on the field for the vast majority of the game. New Minnesota head coach Kevin O’Connell may want to get a better glimpse of the first unit in the second exhibition game.

Pittsburgh Steelers vs. Jacksonville Jaguars best odds

  • When: Sat., Aug. 20, 7 p.m. ET
  • Moneyline: Steelers , Jaguars
  • Spread: Steelers , Jaguars
  • Total:

The Steelers’ first game without Ben Roethlisberger couldn’t have gone better for those vying to replace him. Mason Rudolph and Mitchell Trubisky led scoring drives that culminated in passing TDs, while rookie Kenny Pickett threw a pair of scores. The Jaguars are winless in two preseason games, but new head coach Doug Peterson could look to step it up this week.

Dallas Cowboys vs. Los Angeles Chargers best odds

  • When: Sat., Aug. 20, 10 p.m. ET
  • Watch: NFL Network
  • Moneyline: Cowboys , Chargers
  • Spread: Cowboys , Chargers
  • Total:

The preseason struggles of the Cowboys continue. After going winless last year, the club fell by a score of 17-7 at the Broncos last week. The Chargers were 29-22 losers to their fellow SoFi Stadium tenants, the defending champion Rams. These two clubs are both in the top 10 for the latest Super Bowl futures odds.

Philadelphia Eagles vs. Cleveland Browns best odds

  • When: Sun., Aug. 21, 1 p.m. ET
  • Watch: NFL Network
  • Moneyline: Eagles , Browns
  • Spread: Eagles , Browns
  • Total:

Jalen Hurts threw for a score and didn’t miss a throw in limited time, but the Eagles still lost a field-goal decision to the Jets. Deshaun Watson struggled while on the field for the Browns. The backups fared better as Cleveland picked up a 24-13 victory over the Jaguars. Opening odds have Philadelphia favored, but any line moves could provide clues on playing time.

Cincinnati Bengals vs. New York Giants best odds

  • When: Sun., Aug. 21, 7 p.m. ET
  • Watch: NFL Network
  • Moneyline: Bengals , Giants
  • Spread: Bengals , Giants
  • Total:

Joe Burrow returned to camp after missing time for appendix surgery, but we shouldn’t be surprised if the club plays it cautiously for this one. Cincinnati fell to the Cardinals in its exhibition opener by a score of 36-23. The Giants pulled out a last-minute victory over the Patriots. Daniel Jones and the rest of the first team will probably see more snaps this week.

Baltimore Ravens vs. Arizona Cardinals best odds

  • When: Sun., Aug. 21, 8 p.m. ET
  • Watch: FOX
  • Moneyline: Ravens , Cardinals
  • Spread: Ravens , Cardinals
  • Total:

John Harbaugh’s preseason hot streak continued with a double-digit victory over the Titans. The Cardinals pulled out a 13-point win of their own over the Bengals. Based on that, this one has the chance to be more entertaining than most exhibition games. However, oddsmakers have installed Baltimore as a pretty sizable favorite.

Atlanta Falcons vs. New York Jets best odds

  • When: Mon., Aug. 22, 8 p.m. ET
  • Watch: ESPN
  • Moneyline: Falcons , Jets
  • Spread: Falcons , Jets
  • Total:

Falcons rookie QB Desmond Ridder showed plenty of promise while throwing for two scores in last week’s victory over the Lions. The Jets pulled out a win over the Eagles but also received a big scare when Zach Wilson went down with a knee injury. He’s expected to miss up to a month. Joe Flacco could get some extra time to work with the offense as a result.

NFL Preseason Week 1 betting recap

Through 17 preseason games, it has been a mixed bag of results on the moneyline and spread. However, the over was the clear-cut winner when wagering on the total.

  • Moneyline: Favorites 8-8 with one push
  • Spread: Favorites 9-7 with one push
  • Totals: Overs 14-3

For the Hall of Fame Game and the first full week of the preseason, totals were set in the low to mid-30s across the board. This week, oddsmakers have set the bar higher, with totals currently ranging from a low of 37.5 to a high of 42.5 points.

As for the moneyline and spread, the results help to demonstrate the overall unpredictability of preseason games. For a general rule, pick your spots if you see an advantage and pass when you don’t while always wagering responsibly.

What can you bet on during NFL Preseason?

As mentioned, betting options for preseason games are less than what bettors will find during the regular season. For each game, the big three pregame bets of moneyline, spread, and totals are readily available, while prop betting options are scant.

Playing time for key players during the preseason can be tough to project. Sportsbooks don’t offer player props as a result, and also tend to stay away from game and team props. For those looking for options outside of the pregame lines, here’s what’s typically available.

  • First half: You can bet on the moneyline, spread, and over under for the first half of the game.
  • Same game parlays: Options are limited, but you can put together an SGP with a moneyline or spread plus the over/under.
  • Team scoring: Some sportsbooks offer options on ‘both teams to score X’ number of points.
  • Winning margin: You can try to pinpoint the winning margin, such as ‘Team A to win by 1-6 points.’

Please note that all of the above options will not necessarily be available at every legal online sportsbook or for each of the contests on the docket. Once Week 1 of the regular season is on tap, the menu of available options expands tremendously.

Christopher Feery Avatar
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Christopher Feery

Christopher has been writing professionally for several years, covering sports for multiple outlets along the way. Following the legalization of sports betting in New Jersey in 2018, the industry quickly became his sole content focus. He contributes analysis, guides, and reviews to Legal Sports Report and other sites within the Catena Media network.

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