San Francisco 49ers Odds

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The San Francisco 49ers defeated the Dolphins at home on Sunday for its fifth straight victory. The club remains in outstanding shape when it comes to Super Bowl futures, but also took a huge hit in the victory. Jimmy Garoppolo has been lost for the year to a broken foot, with rookie Brock Purdy the next man up on the depth chart. San Francisco returns to the field in Week 14 with a visit from the 6-6 Tampa Bay Buccaneers. Here’s a closer look at the latest 49ers betting odds and angles.

San Francisco 49ers odds: Spread, moneyline and over/under

Week 14 49ers odds: San Francisco welcomes Buccaneers for NFC showdown

The 49ers were five-point favorites for the visit from the Dolphins. Miami jumped out to a quick 7-0 lead, but it was all San Francisco from there for a 33-17 win. The Buccaneers hosted the Saints on Monday Night Football as three-point favorites. Down 16-3 with just minutes to play, Tom Brady and company roared back to escape with a 17-16 victory.

San Francisco is 7-5 against the spread and 5-7 on totals. Tampa Bay is 3-8-1 ATS and 2-10 on the over/under. The teams last faced off in 2019, a 31-17 road win for the 49ers. For the all-time series, San Francisco leads 18-7.

49ers vs. Buccaneers player props

You can find the latest real-time prop odds by entering the name of the player in the table below. If you come across a bet that you like, click on your selection and you’ll be directed to the sportsbook to place it.

The 49ers are averaging 23.5 points per game and allowing 15.8. After coming on in relief of the injured Jimmy Garoppolo, Brock Purdy threw for 210 yards, two TDs, and a pick. The Buccaneers are scoring an average of 18.1 points per game while giving up 18.3. Tom Brady has thrown for 3,332 yards and 16 scores thus far. 49ers vs. Buccaneers player props will be unveiled by sportsbooks in the coming days.

San Francisco 49ers odds to win the Super Bowl

Last updated: Dec. 6

When DraftKings first released odds on the winner of the next Super Bowl in January, the 49ers were toward the top of the board at +1400. Following an 8-4 start, the team’s odds have moved to . San Francisco has made it to at least the NFC title game in two of the last three seasons. The Buffalo Bills () are among the top favorites to win the 2023 Super Bowl.

San Francisco 49ers futures odds for 2022-23

Beyond wagering on the team to break through and win the big game, you can also bet on the club in other areas. Here are some of the latest futures odds for San Francisco.

The 49ers entered the season as a contender according to odds boards. As we hit the stretch run, that still holds true. San Francisco is in the mix for the NFC West crown and has the potential to make a run to the Super Bowl.

San Francisco 49ers schedule

Week DateOpponentKickoff TimeSpreadMoneylineTotal
1Sept. 11at Chicago Bears1 p.m. ETCHI +6.5
Bears 19-10
Under 38.5
2Sept. 18vs. Seattle Seahawks4:05 p.m. ETSF -8
49ers 27-7
Under 39.5
3Sept. 25at Denver Broncos8:20 p.m. ETDEN +1.5
Broncos 11-10
Under 44.0
4Oct. 3vs. Los Angeles Rams8:15 p.m. ETSF -2
49ers 24-9
Under 42.0
5Oct. 9at Carolina Panthers4:05 p.m. ETSF -6
49ers 37-15
Over 39.5
6Oct. 16at Atlanta Falcons1 p.m. ETATL +3.5
49ers 28-14
Under 45.5
7Oct. 23vs. Kansas City Chiefs4:25 p.m. ETKC -1
Chiefs 44-23
Over 49.0
8Oct. 30at Los Angeles Chargers4:25 p.m. ETPick’em
49ers 31-14
Over 42.0
10Nov. 13vs. Los Angeles Chargers8:20 p.m. ETLAC +8
49ers 22-16
Under 45.5
11Nov. 21vs. Arizona Cardinals (in Mexico City)8:15 p.m. ETSF -9.5
49ers 38-10
Over 43.0
12Nov. 27vs. New Orleans Saints4:25 p.m. ETSF -8.5
49ers 13-0
Under 43.5
13Dec. 4vs. Miami Dolphins4:05 p.m. ETSF -5
49ers 33-17
Under 45.5
14Dec. 11vs. Tampa Bay Buccaneers4:25 p.m. ETTB +3.5 (-110)
SF -3.5 (-110)
Buccaneers (+150)
49ers (-175)
37.5 (-110)
15Dec. 15at Seattle Seahawks8:15 p.m. ET
16Dec. 25vs. Washington Commanders4:05 p.m. ET
17Jan. 1at Las Vegas Raiders4:05 p.m. ET
18Jan. 8vs. Arizona CardinalsTBD

Latest news and updates

The 49ers ran their winning streak to five games with a double-digit win over the visiting Dolphins on Sunday. The club continues to gain attention as a potential Super Bowl contender, and it appears poised to battle it out with the Seahawks for the NFC West title. Jimmy Garoppolo went down to a season-ending foot injury in the victory over Miami. Brook Purdy took over in his absence and played well. The team appears set to roll with the rookie under center the rest of the way. San Francisco returns to action on Sunday when it hosts the Buccaneers.

Other teams in the NFC

NFC EastDallas CowboysNY GiantsPhiladelphia EaglesWashington Commanders
NFC NorthChicago BearsDetroit LionsMinnesota VikingsGreen Bay Packers
NFC SouthAtlanta FalconsCarolina PanthersNew Orleans SaintsTampa Bay Bucs
NFC WestArizona CardinalsLA RamsSan Francisco 49ersSeattle Seahawks

San Francisco 49ers FAQ

Are the 49ers a Super Bowl contender this season?

Yes. The 49ers could contend for the Super Bowl, at least according to the latest odds. The Bills are among the other favorites to win the big game.

How did the 49ers do against the spread last year?

The 49ers were 12-8 against the spread last season, which was one of the five best records in the league on that metric. The team went 12-8 on the moneyline and 8-12 on totals.

Whom did the 49ers add and lose in the offseason?

The main signing was Charvarius Ward in free agency, while Laken Tomlinson and D.J. Jones were among those moving on. The team’s first pick in the NFL draft was Drake Jackson in round two.

Who is the 49ers starting QB this year?

Brock Purdy is now the QB1 in the wake of Jimmy Garoppolo suffering a season-edning foot injury. Trey Lance began the year as the starter, but his season was ended with an ankle injury in Week 2.

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