The San Francisco 49ers are one of the top betting favorites to win Super Bowl 58. The team has made it to the conference title game three times in the last four years but has only appeared in one Super Bowl over that span, and that was a loss. San Francisco will be on the road in Week 1 against the Pittsburgh Steelers. Here’s a closer look at the latest 49ers betting odds and angles.
San Francisco 49ers odds: Spread, moneyline and over/under
Below are the latest odds for the next 49ers game. Clicking on the odds will bring you directly to the sportsbook where you can place your wager.
Week 1 odds: 49ers open on road at Steelers
The 49ers were the NFC West champions last season with a record of 13-4. The team advanced to the conference title game before falling to the Eagles as injuries at QB proved to be far too much to overcome. For the year, the club went 15-5 on the moneyline, 13-7 against the spread and 10-10 on the over/under.
- Point spread: 49ers . Steelers
- Moneyline: 49ers , Steelers
- Total: Over/under
The Steelers finished last season at 9-8. The club was solid down the stretch, winning seven of its last nine to rebound from a challenging 2-6 start to the campaign. Pittsburgh had a record of 10-6-1 ATS and 7-10 on totals.
49ers vs. Steelers player props
Last season, the 49ers scored an average of 25.9 points per game and allowed 17.2. The team had a revolving door at QB. Trey Lance and Jimmy Garoppolo both went down to injury. Rookie Brock Purdy took over and played extremely well to lead the club to the postseason. He suffered a UCL tear during the NFC title game and will miss about six months. Christian McCaffrey topped the team in rushing with 746 yards, while Brandon Aiyuk led the receivers with 1,015. We’ll list 49ers vs. Steelers player props here once they become available.
San Francisco 49ers odds to win the Super Bowl
Last updated: June 1
DraftKings released odds on the winner of Super Bowl 58 in January 2023. At the time, San Franciso was at +800. The 49ers’ current odds to win the 2024 Super Bowl are . The club made it to the playoffs last season, losing to the Eagles in the NFC championship game. The franchise is 5-2 in all-time big game appearances, losing its last trip to the Chiefs at Super Bowl LIV.
San Francisco 49ers futures odds for 2023-24
The winner of Super Bowl 58 is the star attraction in NFL futures bets, but there are other options, as well. The lines for many of them come out over the offseason, and a couple are already available. Here are the latest 49ers futures odds for the upcoming season.
- To win the NFC:
- To win the NFC West:
- Regular season win total:
- Brock Purdy MVP odds:
San Francisco 49ers schedule
Below is the 49ers’ schedule for the 2023-24 regular season. We will update betting lines and results as the season progresses.
| Week | Date | Opponent | Kickoff | Spread | Moneyline | Total |
| 1 | Sept. 10 | at Pittsburgh Steelers | 1 p.m. ET | |||
| 2 | Sept. 17 | at Los Angeles Rams | 4:05 p.m. ET | |||
| 3 | Sept. 21 | vs. New York Giants | 8:15 p.m. ET | |||
| 4 | Oct. 1 | vs. Arizona Cardinals | 4:25 p.m. ET | |||
| 5 | Oct. 8 | vs. Dallas Cowboys | 8:20 p.m. ET | |||
| 6 | Oct. 15 | at Cleveland Browns | 1 p.m. ET | |||
| 7 | Oct. 23 | at Minnesota Vikings | 8:15 p.m. ET | |||
| 8 | Oct. 29 | vs. Cincinnati Bengals | 4:25 p.m. ET | |||
| 9 | BYE | |||||
| 10 | Nov. 12 | at Jacksonville Jaguars | 1 p.m. ET | |||
| 11 | Nov. 19 | vs. Tampa Bay Buccaneers | 4:05 p.m. ET | |||
| 12 | Nov. 23 | at Seattle Seahawks | 8:20 p.m. ET | |||
| 13 | Dec. 3 | at Philadelphia Eagles | 4: 25 p.m. ET | |||
| 14 | Dec. 10 | vs. Seattle Seahawks | 4:05 p.m. ET | |||
| 15 | Dec. 17 | at Arizona Cardinals | 4:05 p.m. ET | |||
| 16 | Dec. 25 | vs. Baltimore Ravens | 8:15 p.m. ET | |||
| 17 | Dec. 31 | at Washington Commanders | 1 p.m. ET | |||
| 18 | Jan. 7 | vs. Los Angeles Rams | TBD |
Latest news and updates
The 49ers opened the postseason with victories over the Seahawks and Cowboys, but their run ended with a road loss to the Eagles in the NFC title game. Injuries played a big part in the defeat, as Brock Purdy suffered a torn UCL. Defensive coordinator DeMeco Ryans is now the new head coach of the Texans, and San Francisco has hired Steve Wilks, most recently the interim head coach of the Panthers, to take his place. The 49ers have further bolstered their defense with the signing of DT Javon Hargrave, formerly of the Eagles, to a four-year, $84 million deal.
San Francisco 49ers draft picks
The 49ers were not on the clock until round three of this year’s NFL draft. The club had a trio of selections in round three, selecting S Ji’Ayir Brown of Penn State, K Jake Moody from Michigan and Alabama TE Cameron Latu. The team had six more picks the rest of the way, using one of them on South Alabama CB Darrell Luter Jr.
Other teams in the NFC
San Francisco 49ers FAQ
Are the 49ers a Super Bowl contender this season?
Sportsbooks view San Francisco as a top contender to win Super Bowl 58. At the initial release of 2024 Super Bowl futures odds, the club was one of the top four options on the board.
How did the 49ers do against the spread last season?
The 49ers were 13-7 against the spread, 15-5 on the moneyline and 10-10 on totals for the 2022-23 season.
Whom did the 49ers add and lose in the offseason?
Among the 49ers’ acquisitions have been Javon Hargrave and Sam Darnold via free agency. Players who have moved on from San Francisco include Mike McGlinchey and Jimmy Garoppolo. At the NFL draft, the team’s top selection was Ji’Ayir Brown in round three.
Who is the 49ers’ starting QB this year?
Brock Purdy finished the season as QB1 in the wake of Jimmy Garoppolo suffering a foot injury. Trey Lance began the year as the starter, but his season ended with an ankle injury in Week 2. The club has also added Sam Darnold in free agency. The starter for Week 1 has not been announced.