Don’t blink; we’ve only got two more regular season weeks left of college football betting in 2024. In mid-November, the conversation shifts to the big picture, specifically conference championship races, the Heisman Trophy, and the College Football Playoff. Just four teams are on byes this week: Navy, New Mexico, Oregon, and Washington. This is the busiest week of college football since September, and, though it doesn’t have the glamor of Rivalry Week, this coming weekend will shape the postseason race significantly. Odds for every college football game this weekend are available below.
Top billing goes to a suddenly blockbuster matchup in the Big Ten between top-five Ohio State and Indiana. Ole Miss travels to Florida with a resurgent star QB in D.J. Lagway, looking to dash the playoff hopes of the Rebels. Army versus Notre Dame is now must-see TV between two ranked teams in the Bronx. Kansas looks to bounce Colorado from the Big 12 championship race and keep its bowl game hopes alive.
Also, watch for two former Pac-12 rivalries: The Big Game (Cal vs. Stanford) and USC vs. UCLA. A handful of big games could affect conference championship races, as well, including NIU vs. Miami (OH) and Ohio vs. Toledo in the MAC, and Sam Houston State at Jacksonville State in Conference USA.
College football Week 13 odds: Spreads, moneylines, totals
College football Week 13 opening odds: Spreads, lines, totals
| Date | Game | Opening Spread | Opening Total |
|---|---|---|---|
| Nov. 19 | Akron at Kent State | AKR -9.5 | 50 |
| Nov. 19 | Western Michigan at Central Michigan | WMU -7.5 | 54 |
| Nov. 19 | Northern Illinois at Miami (OH) | M-OH -3.5 | 44 |
| Nov. 20 | Ohio at Toledo | TOL -3 | 51 |
| Nov. 20 | Buffalo at Eastern Michigan | EMU -1.5 | 54 |
| Nov. 21 | NC State at Georgia Tech | GT -9.5 | 53 |
| Nov. 22 | Temple at UTSA | UTSA -15.5 | 56 |
| Nov. 22 | Purdue at Michigan State | MSU -14.5 | 48.5 |
| Nov. 22 | UNLV at San Jose State | UNLV -7.5 | 63.5 |
| Nov. 23 | No. 14 SMU at Virginia | SMU -9.5 | 58 |
| Nov. 23 | Sam Houston at Jacksonville State | JAX -6.5 | 55 |
| Nov. 23 | Wake Forest at No. 9 Miami (FL) | MIA -24 | 65 |
| Nov. 23 | North Carolina at Boston College | UNC -3.5 | 56 |
| Nov. 23 | No. 11 Ole Miss at Florida | MISS -6.5 | 55.5 |
| Nov. 23 | UConn at Syracuse | SYR -11.5 | 54 |
| Nov. 23 | Iowa at Maryland | IOWA -7 | 45.5 |
| Nov. 23 | No. 5 Indiana at No. 2 Ohio State | tOSU -11.5 | 51.5 |
| Nov. 23 | Illinois at Rutgers | RUT -1 | 47 |
| Nov. 23 | UMass at No. 12 Georgia | UGA -45.5 | 57 |
| Nov. 23 | Western Kentucky at Liberty | WKU -1 | 56.5 |
| Nov. 23 | UTEP at Tennessee | TEN -41.5 | 55 |
| Nov. 23 | Bowling Green at Ball State | BGSU -10 | 58 |
| Nov. 23 | Rice at UAB | RICE -6.5 | 51 |
| Nov. 23 | James Madison at Appalachian State | JMU -7 | 60.5 |
| Nov. 23 | New Mexico State at Middle Tennessee | MTSU -4.5 | 50.5 |
| Nov. 23 | Charlotte at FAU | PK | 47.5 |
| Nov. 23 | FIU at Kennesaw State | FIU -9.5 | 44 |
| Nov. 23 | Arizona at TCU | TCU -9.5 | 58.5 |
| Nov. 23 | South Alabama at Southern Miss | USA -21.5 | 55.5 |
| Nov. 23 | ULM at Arkansas State | ARST -5 | 52 |
| Nov. 23 | Georgia Southern at Coastal Carolina | CCU -1.5 | 57 |
| Nov. 23 | UCF at West Virginia | UCF -2.5 | 64.5 |
| Nov. 23 | No. 17 Colorado at Kansas* | CU -2.5 | 59.5 |
| Nov. 23 | Tulsa at USF | USF -14 | 59.5 |
| Nov. 23 | Wisconsin at Nebraska | NEB -1.5 | 42.5 |
| Nov. 23 | No. 4 Penn State at Minnesota | PSU -10 | 46 |
| Nov. 23 | Northwestern at Michigan | MICH -13.5 | 38.5 |
| Nov. 23 | San Diego State at Utah State | USU -4.5 | 62.5 |
| Nov. 23 | No. 6 BYU at Arizona State | ASU -1 | 49 |
| Nov. 23 | Stanford at Cal | CAL -13 | 55.5 |
| Nov. 23 | Kentucky at No. 3 Texas | TEX -21 | 46.5 |
| Nov. 23 | Texas Tech at Oklahoma State | TTU -4 | 68.5 |
| Nov. 23 | East Carolina at North Texas | ECU -2.5 | 72.5 |
| Nov. 23 | Pitt at No. 19 Louisville | LOU -7.5 | 56.5 |
| Nov. 23 | Louisiana Tech at Arkansas | ARK -23.5 | 50.5 |
| Nov. 23 | No. 23 Missouri at Mississippi State | MIZ -6.5 | 56.5 |
| Nov. 23 | Troy at Louisiana | ULL -10.5 | 53 |
| Nov. 23 | Georgia State at Texas State | TXST -17 | 58.5 |
| Nov. 23 | Baylor at Houston | BAY -6.5 | 50 |
| Nov. 23 | No. 13 Boise State at Wyoming | BSU -22.5 | 57.5 |
| Nov. 23 | No. 18 Washington State at Oregon State | WAZ -12.5 | 56.5 |
| Nov. 23 | No. 24 Army vs. No. 8 Notre Dame* | ND -15.5 | 43.5 |
| Nov. 23 | Marshall at Old Dominion | MAR -2 | 51.5 |
| Nov. 23 | Iowa State at Utah | UTAH -10^ | 43 |
| Nov. 23 | No. 15 Texas A&M at Auburn | A&M -3.5 | 47 |
| Nov. 23 | No. 10 Alabama at Oklahoma | BAMA -2^ | 48.5 |
| Nov. 23 | Vanderbilt at No. 22 LSU | LSU -11 | 54.5 |
| Nov. 23 | Virginia Tech at Duke | VT -2.5 | 48.5 |
| Nov. 23 | Cincinnati at No. 16 Kansas State | KST -8.5 | 52.5 |
| Nov. 23 | Air Force at Nevada | NEV -3.5 | 45.5 |
| Nov. 23 | USC at UCLA | USC -4.5 | 50.5 |
| Nov. 23 | Colorado State at Fresno State | FRES -1 | 50.5 |
^Notes Game of the Year odds opened in the summer.
Note: College football odds move frequently; be sure to shop around at available sportsbooks to get the best odds for any bet you wish to place. Couple odds with the best college football betting promotions to maximize your winnings. Check back every week for college football updates.
College football Week 13 game odds and analysis
No. 5 Indiana at No. 2 Ohio State, 12 p.m. (Fox)
What might have been a four-touchdown spread back in July is now one of the premier matchups in the Big Ten this season. Not only has Indiana never started 10-0 in program history, it’s never won 10 games in a season. Curt Cignetti received an eight-year contract extension as a result of his first-year success.
Only Ohio State and Notre Dame have a bigger average point margin this season than the Hoosiers (+25.2). That result is thanks to the fourth-ranked offense in points per drive, led by transfer QB Kurtis Rourke, and the 12th-ranked defense in points per drive, headed by a roster largely imported from James Madison last year. Indiana may have opportunities through the air as Ohio State’s secondary, touted though it is, gives up big plays while in man coverage.
On the other side, Ohio State (9-1) is third in the nation both in points per drive on offense and defense. Watch to see how a rebuilt Buckeyes offensive line fares — so far, All-American guard Donovan Jackson, now at left tackle, has held up pretty well, as has the rest of the reshuffled unit. Many power ratings systems this week feature Ohio State as the top team in the country.
- Opening odds: Ohio State -11.5, O/U 51.5
No. 11 Ole Miss at Florida, 12 p.m. (ABC)
Ole Miss comes off a week of rest after upsetting Georgia in front of a record-breaking crowd in Oxford. Florida just had its own emotional win, beating LSU as +3 home ’dogs last week. Gators freshman QB D.J. Lagway returned from injury and played another dynamic game.
Right now, Florida built the whole plane out of Lagway. It’s been largely an effective strategy, as Florida hung with Georgia until the QB exited with an injury. A mismatch to watch is the Gators’ often chaotic way of offense — they rank near the bottom of the country in havoc plays forfeited (think tackles for loss and turnovers) — against Ole Miss’ top-flight defensive front. Walter Nolen and Princely Umanmielen are both All-SEC performers, if not All-American.
The Rebels may be able to take advantage of large chunk plays in the Swamp, as well. Receiver Jordan Watkins emerged as a weapon in the absence of star Tre Harris, who hasn’t played since Week 7. QB Jaxson Dart leads one of the most efficient and explosive offenses in the country this season.
- Opening odds: Ole Miss -6.5, O/U 55.5
Sam Houston at Jacksonville State, 12 p.m. (CBSSN)
OK, maybe this one won’t have the grandeur and exploding crowds of others in Week 13, but Sam Houston at Jacksonville State might have the most direct impact on conference championship games of any, save for Indiana-Ohio State. Sam Houston is 5-1 in Conference USA play, and Jacksonville State is a game ahead at 6-0. The three-horse race, along with Western Kentucky, is far from over — even 4-2 Liberty has hopes of playing in it — and this game will be a banner finish for either team.
The Gamecocks had a big win over Liberty followed by two rocky games: overtime against Louisiana Tech (3-5 coming in) and a three-point victory over FIU (3-6 coming in). Their defense faltered, allowing 68 combined points in the two contests.
Perhaps Jacksonville State’s recent defensive form is the fix for the common offense — something Sam Houston sorely needs. The Bearkats, in their last four games, failed to crack 20 points in regulation and drew to 10-7 and 9-3 finishes (not records, scores). WKU holds the direct tiebreaker, but a win Saturday would make it Sam Houston vs. WKU for the title, assuming all parties win out.
- Opening odds: Jacksonville State -6.5, O/U 55
No. 17 Colorado at Kansas, 3:30 p.m. (Fox)
What in the preseason appeared to be a fun matchup fizzled into what could be a blowout and then has rebounded back to being a matchup of interest in Week 13. Kansas is firmly out of the Big 12 Conference race (in fact, a loss here would eliminate the Jayhawks from bowl eligibility). Colorado, meanwhile, sits in the driver’s seat, currently the odds-on favorite to win the conference with a heavy favorite in Heisman Trophy odds.
The Buffs are on a mission, but don’t discount the recent form of the Jayhawks. Kansas won three of its last four games and nearly all four, barely losing to rival Kansas State, going 4-0 ATS in the process. QB Jalon Daniels has cut down on the turnovers significantly. He threw eight interceptions in his first five games and just two in his latest five. The Kansas rushing attack is back on track, rushing for 200+ yards in three of its last four outings.
Colorado’s biggest surprise this year isn’t its Heisman favorite in Travis Hunter, but rather the defensive unit. Last season, the Buffs finished 117th in points per drive surrendered; that’s up to 34th this season. While Colorado’s rushing defense has been largely airtight this year, the Buffs have been unable to run the ball. Shedeur Sanders will have to air it out this week again, which plays into the strength of the Kansas defense: its star secondary led by Cobee Bryant and Mello Dotson.
This game is played at Arrowhead Stadium while the Jayhawks await a massive renovation of their home stadium.
- Opening odds: Colorado -2.5, O/U 59.5
No. 24 Army vs. No. 12 Notre Dame, 7:30 p.m. (NBC)
Army remains one of just three remaining unbeaten FBS teams (Oregon, Indiana). The Black Knights survived their last game two weeks ago against North Texas despite returning star QB Bryson Daily. Could this be the week Army shows its cracks, as rival Navy did against Notre Dame a few weeks ago?
While not the No. 1 offense in total points or yards, Army finishes its drives with more points than any team in the nation, on par with teams like 2023 Oregon, 2020 BYU, and 2019 LSU. That, of course, is led by the top rushing attack in the nation by over 70 yards (330 yards per game). Daily is second among QBs with 1,063 rushing yards and 14th among all players; his 21 rushing touchdowns rank second in the nation (first is — who else — Ashton Jeanty).
Notre Dame offers a stiff test defensively despite a rash of injuries. Watch for the availability of All-America defensive tackle Howard Cross, who missed Week 11 and was limited last week to just 27 snaps. The Irish flexed their muscles against previously unbeaten Navy in a 51-13 blowout that’s led to three losses in four outings for the Midshipmen. Notre Dame certainly out-physicals Army, which means the Black Knights may need to get creative to stay in this game.
Note: This game will be at Yankee Stadium in the Bronx as a part of Notre Dame’s annual Shamrock Series.
- Opening odds: Notre Dame -15.5, O/U 43.5
