2023 NFL Week 4 Odds: Spreads, Totals, Props For Every Game

Written By

Last Updated

Week 4 of the 2023 NFL season kicks off with an NFC North battle between the Detroit Lions and Green Bay Packers on Thursday, Sept. 28. This intriguing matchup features the preseason division favorite Lions looking to hold off the new-look Packers.

Other spotlight games on the following Sunday include the New England Patriots playing the Dallas Cowboys, and then the Kansas City Chiefs traveling to New Jersey to take on the New York Jets. This is also the first week where an early international game will take place.

NFL Week 4 updated odds and lines

Here are the most current lines for NFL week 4. We have totals, spreads, and moneylines.

NFL Week 4 spread odds

NFL Week 4 moneyline odds

NFL Week 4 over/under odds

Top sportsbooks for NFL Week 4 odds

All the best sports betting sites we recommend feature Week 4 NFL odds. The betting market features typical game lines and various props for teams and players. New customers can check out the available welcome promos if they sign up to place a bet at any of the books below.

UP TO $1,000
In Bonus Bets
Top Features
First Bet Safety Net up to $1,000, or 
Bet $5, Get $150 in Bonus Bets
Gambling Problem? Call 1-800-Gambler 21+ 
Use Bonus Code: LSRVA
New Users Get up to $1,000 Bonus at Bet365
UP TO $250
Bonus Bet with First Wager
Top Features
First Bet Reset Up to $250 Back in Bonus Bets
Get Betway Boosts & Enhanced Odds
To Claim: Click Play Now
Claim your $250 Bonus Bet at Betway Sportsbook!
UP TO $1,500
In Bonus Bets
Top Features
$1,500 Paid Back in Bonus Bets
Free Live Streaming – Watch Live Games 
Use Bonus Code: PLAYLSR
Get Up to $1,500 Paid Back in Bonus Bets
$1,000 FIRST BET
On Caesars
Top Features
Up to $1,000 Bonus Bet if Your Bet Loses
Stream NFL Games In-App for Free
21+ Gambling problem? Call 1-800-GAMBLER
Use Promo Code: LSR1000
Get up to $1,000 at Caesars Sportsbook
Bet $5
Get $150
In Bonus Bets
Top Features
Up to $150 in Bonus Bets if Your Team Wins
Available on Desktop, Android & iOS
To Claim: Click Play Now
New Players get up to $150 in Bonus Bets at FanDuel Sportsbook
$100 Bonus
No Regret First Bet
Top Features
Up to $100 Back if Your First Bet Doesn’t Hit
Get Your Bets Boosted
To Claim: Click Play Now
Sign Up at Hard Rock Bet Sportsbook Today!
$500 BONUS
2nd Chance Bet
Top Features
Up To $500 in Bet Credits
ONLY 1x Play Through!
Use Exclusive Bonus Code: LSRRIV
Get Up to $500 Bonus At BetRivers Sportsbook!

NFL Week 4 matchups and best odds

The international series begins with the Atlanta Falcons taking on the Jacksonville Jaguars at Wembley Stadium in London. Nine games on Sunday will begin at 1 p.m. ET, and then three more games will follow in the late afternoon.

Detroit Lions at Green Bay Packers

Thursday Night Football, 8:15 p.m. ET, Prime Video

The Detroit Lions remain the favorites in the NFC North after a 2-1 start. They were missing several starters in Week 3 against the Falcons, including starting linemen Taylor Decker, Halapoulivaati Vaitai, lead running back David Montgomery, and starting defensive backs Kerby Joseph and Emmanuel Moseley.

The Green Bay Packers have been dealing with injuries to their key skill players with Christian Watson (hamstring) and Aaron Jones (hamstring) both out the past two weeks. Jordan Love posted the best passer rating in the NFL over his first two starts this season.

Atlanta Falcons vs. Jacksonville Jaguars

Sunday, 9:30 a.m. ET, ESPN+

The Atlanta Falcons have an improved defense and a strong running game that revolves around rookie Bijan Robinson and second-year back Tyler Allgeier. They head to London after losing, 23-3, in Detroit last week with Desmond Ridder absorbing seven sacks.  

The Jacksonville Jaguars have already played more games (9) in London than any other NFL team and this the first of two games they will play in London this season. The Jags entered this season as the prohibitive favorites to win the AFC South, but they’ve struggled during a 1-2 start.

Miami Dolphins at Buffalo Bills

Sunday, 1 p.m. ET, CBS

The Buffalo Bills dropped their opener at the Jets, then bounced back with blowout wins over the Raiders and Commanders by a combined margin of 75-13. Buffalo has won three straight AFC East titles and is now a slight underdog to win the division with the Dolphins (-160) in first place at 3-0. 

The Miami Dolphins became the first team since 1966 to break 70 points in a NFL game and set a new record with 726 total yards in their home opener. Tua Tagovailoa is the early frontrunner for MVP and Tyreek Hill is an early leader for Offensive Player of the Year. Veteran Raheem Mostert and rookie De’Von Achane provide speed out of the backfield.

Denver Broncos at Chicago Bears

Sunday, 1 p.m. ET, CBS

The Denver Broncos are 5-15 since the start of last season and have lost all three games so far under new coach Sean Payton. Their defense has allowed 105 points and 1,114 total yards over their last two defeats. 

The Chicago Bears have been maligned on both sides of the ball during an 0-3 start. Justin Fields appeared to suffer a concussion during a blowout loss at Kansas City, but was cleared to return and finished the game.

Baltimore Ravens at Cleveland Browns

Sunday, 1 p.m. ET, CBS

The Baltimore Ravens are dealing with injuries to linemen Ronnie Staley and Mark Lindenbaum and defensive backs Marcus Williams and Marlon Humphrey. This is the first of consecutive division road games for Baltimore, which heads to Pittsburgh in Week 5.

The Cleveland Browns have been dominant defensively through three games with just 10.7 PPG allowed and nine sacks. They lost all-pro back Nick Chubb to a season-ending knee injury and brought Kareem Hunt back to work alongside Jerome Ford.

Cincinnati Bengals at Tennessee Titans

Sunday, 1 p.m. ET, Fox

The Cincinnati Bengals avoided an 0-3 start with a close win over the Rams to end Week 3. With Joe Burrow limited by a calf injury, their offense is averaging 14.7 points and 244.3 yards per game. 

The Tennessee Titans are struggling to protect Ryan Tannehill or run-block for Derrick Henry. The Titans have averaged 15 PPG while converting on 27% of third downs during a 1-2 start.

Los Angeles Rams at Indianapolis Colts

Sunday, 1 p.m. ET, Fox

The Los Angeles Rams are averaging the fourth-most passing yards per game (284) despite the absence of Cooper Kupp (hamstring). Rookie Puka Nacua and second-year receiver Tutu Atwell have picked up the slack and Kyren Williams is their new lead back. 

The Indianapolis Colts rallied for an overtime win in Baltimore without rookie quarterback Anthony Richardson (concussion). Zack Moss has been filling in as the lead back with Jonathan Taylor (ankle) inactive through the first four weeks.

Tampa Bay Buccaneers at New Orleans Saints

Sunday, 1 p.m. ET, Fox

The Tampa Bay Buccaneers pulled out a couple of close wins to open the season with Baker Mayfield taking over at quarterback. The Bucs committed their first two turnovers of the season on Monday night and suffered their first loss at the hands of the NFC champion Eagles. 

The New Orleans Saints entered the season as the favorites to win the NFC South with Derek Carr taking over at quarterback. Carr injured his shoulder in Week 3 and Jameis Winston stepped in. Alvin Kamara is eligible to return from suspension in Week 4.

Washington Commanders at Philadelphia Eagles

Sunday, 1 p.m. ET, Fox

After an impressive second half comeback at Denver, the Washington Commanders suffered a 37-3 home loss against the Bills in Week 3. Sam Howell has taken 19 sacks and thrown five interceptions through three starts this season. 

The Philadelphia Eagles lost both offensive coordinator Shane Steichen and defensive coordinator Jonathan Gannon to head coaching jobs after advancing to the Super Bowl last season. Their rushing attack has become very productive over their last two wins with D’Andre Swift leading the way.

Minnesota Vikings at Carolina Panthers

Sunday, 1 p.m. ET, CBS

The Minnesota Vikings have dropped three one-score games to open this season after winning a record 11 one-score games last year. Newly acquired back Cam Akers will split backfield duties with Alexander Mattison once he becomes acclimated to a new offense. 

With Bryce Young unavailable, the Carolina Panthers turned to veteran Andy Dalton in a loss at Seattle. Adam Thielen posted 145 receiving yards in the loss, his highest total since September 11, 2017, during his fourth of nine seasons with the Vikings.

Pittsburgh Steelers at Houston Texans

Sunday, 1 p.m. ET, CBS

The Pittsburgh Steelers opened this season with their worst home loss in 16 years. They’ve rebounded with a pair of close wins thanks to elite defensive play from T.J. Watt, Minkah Fitzpatrick, and others. George Pickens has tallied 202 receiving yards in those wins with veteran Diontae Johnson (hamstring) on I.R. 

The Houston Texans continued to get the better of the Jaguars in that divisional matchup. Rookie C.J. Stroud has been efficient in his last two starts with fellow rookie Tank Dell serving as one of his top targets.

Las Vegas Raiders at Los Angeles Chargers

Sunday, 4:05 p.m. ET, CBS

The Las Vegas Raiders had a strong ground game last year that allowed Josh Jacobs to rush for a league-best 1,653 yards at a 4.9 yards per carry clip. After holding out during training camp, Jacobs is only averaging 2.4 YPC and 36 rushing yards per game during a 1-2 start.

The Los Angeles Chargers got in the win column in Minnesota thanks to a career-best performance from Keenan Allen (18 receptions, 215 yards) and 404 passing yards from Justin Herbert. Cornerback J.C. Jackson was a healthy scratch in the win. Austin Ekeler (ankle) and linebacker Eric Kendricks (hamstring) missed a second straight game.

New England Patriots at Dallas Cowboys

Sunday, 4:25 p.m. ET, Fox

The New England Patriots started 0-2 for the first time in 22 seasons, then won a 15th consecutive game against the Jets. The Patriots have a strong interior defensive line and seem to have found a star cornerback thru the draft in No. 17 overall pick Christian Gonzalez

The Dallas Cowboys lost cornerback Trevon Diggs (ACL) for the season in practice leading up to Week 3. Starting center Tyler Biadasz (hamstring) and guard Zack Martin (ankle) were both inactive when Dallas dropped a surprising decision at Arizona.

Arizona Cardinals at San Francisco 49ers

Sunday, 4:25 p.m. ET, Fox

The Arizona Cardinals came into this season with the lowest projected win total in the NFL. Yet the Cardinals nearly won both of their first two games and stunned the Cowboys in Week 3 after being listed as 12-point underdogs at home. It appears Josh Dobbs will hold down the offense until Kyler Murray (ACL) returns. 

The San Francisco 49ers have cruised to three wins to open the season behind a prolific offense that is averaging 399 total yards and 30.3 points per game. They are favored to win the NFC and have slightly shorter odds than the defending champion Chiefs to win the Super Bowl. 

Kansas City Chiefs at New York Jets

Sunday Night Football, 8:20 p.m. ET, NBC

The Kansas City Chiefs dominated defensively in a Week 2 win at Jacksonville and erupted on offense while building a 41-0 lead over the Bears in Week 3. Travis Kelce (knee) appears to be over his injury and reigning MVP Patrick Mahomes is reportedly fine after hobbling a bit on his ankle during the win. 

The New York Jets have struggled offensively this season with Zach Wilson thrust into the starting role following Aaron Rodgers’ season-ending Achilles injury. They placed tackle Duane Brown (hip) on I.R. and were missing safety Tony Adams (hamstring) during another loss to New England.

Seattle Seahawks at New York Giants

Monday Night Football, 8:15 p.m. ET, ESPN

The Seattle Seahawks lost both starting tackles during their opener and managed just 12 total yards in the second half of a 30-13 loss to the Rams. Since then, they’ve produced 818 total yards with 55 first downs in a pair of high-scoring wins over the Lions and Panthers. Safety Jamal Adams (quad) is expected to make his season debut in Week 4. 

The New York Giants took a blowout loss at San Francisco last Thursday, which gives them a longer week to prepare for a Monday Night home game. Saquon Barkley (ankle) is questionable to return from a one-game absence.

Week 4 player props

NFL bettors have a lot to choose from when it comes to team and player props, including touchdown props and receiving props. To peruse the options, you can select a type of prop bet via the drop-down menu below. When this NFL week nears, the table will show game-specific props.

In the meantime, the odds in the table are for total touchdowns from a skill player for the season. If you wish to place a bet, you can click on the odds to head to the sportsbook offering that wager.

More NFL weekly odds content

Find more odds for every NFL week as well as detailed analysis and breakdowns.