2023 NFL Week 16 Odds: Spreads, Moneylines, And Totals For Every Game

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Another week of the NFL season is in the books, so it’s time to look ahead to the Week 16 matchups around the league. Sportsbooks have released odds on every upcoming game, including when the New York Giants take on the Philadelphia Eagles on Christmas Day.

Here’s a look ahead at odds for all the upcoming games this week, consisting of spreads, moneylines, and point totals at legal US sportsbooks.

NFL Week 16 updated odds and lines

NFL Week 16 point spreads

NFL Week 16 moneyline odds

NFL Week 16 over/under lines

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NFL Week 16 betting breakdown

New Orleans Saints at Los Angeles Rams

Thursday, 8:15 p.m. ET, Prime Video

The New Orleans Saints handled the Panthers and Giants at home to keep pace for the NFC South title, and they’re currently tied atop the division with the Bucs. They’re dealing with multiple injuries on both sides of the ball, with top receiver Chris Olave (ankle) questionable on a short week. 

The Los Angeles Rams have won four of their last five games, and with Kyren Williams (ankle) back for their last four contests, they’ve averaged 427.8 yards and 33 points per game. 

Cincinnati Bengals at Pittsburgh Steelers

Saturday, 4:30 p.m. ET, NBC

The Cincinnati Bengals survived in overtime with a 27-24 victory over the Vikings at home on Saturday. Jake Browning has led the team to three straight wins, but he might be without Ja’Marr Chase (shoulder) in this contest, and the defense lost D.J. Reader (quad) for the season. 

The Pittsburgh Steelers continued to backslide for a third straight loss Saturday at Indianapolis. They’re averaging just 13.7 points and 265.7 yards per game over their last three losses, and Kenny Pickett (ankle) is questionable to return from a two-game absence. 

Buffalo Bills at Los Angeles Chargers

Saturday, 8 p.m. ET, Peacock

The Buffalo Bills may have saved their season with consecutive clutch wins over the Chiefs and Cowboys. Josh Allen has shifted from a long shot to a viable MVP contender, and the Bills have a chance to not only make the playoffs, but to win the AFC East if they can beat the Dolphins in their Week 18 finale. 

The Los Angeles Chargers lost Justin Herbert (finger) for the season and then took a historically bad loss, 63-21, at the Raiders on Thursday, leading to the dismissal of head coach Brandon Staley and GM Tom Telesco. Outside linebackers coach Giff Smith is the interim coach. 

Indianapolis Colts at Atlanta Falcons

Sunday, 1 p.m. ET, Fox 

The Indianapolis Colts bullied the Steelers with 170 rushing yards in Saturday’s win despite losing Zack Moss (arm) in the first quarter. They could get Jonathan Taylor (thumb) back from a three-game absence for this road game. 

The Atlanta Falcons have dropped consecutive divisional matchups after starting 3-0 in games against the NFC South. Desmond Ridder threw a costly pick, and Bijan Robinson was a non-factor in their 9-7 defeat at Carolina in Week 15. 

Seattle Seahawks at Tennessee Titans

Sunday, 1 p.m. ET, CBS 

The Seattle Seahawks will be on a short week in this spot after hosting the Eagles on Monday Night Football. Seattle had lost five of six games heading into Monday and is falling out of the NFC wild card picture with Geno Smith (groin) hobbled.

The Tennessee Titans have dropped consecutive home games after starting 4-0 there this season. Ryan Tannehill appears likely to start at quarterback after Will Levis suffered a high-ankle sprain during an overtime loss to the Texans. 

Detroit Lions at Minnesota Vikings

Sunday, 1 p.m. ET, Fox 

The Detroit Lions got center Frank Ragnow (knee) and got firing on all cylinders in a 42-17 home win over the Broncos on Saturday. Jared Goff passed for 278 yards and five touchdowns in the victory.

The Minnesota Vikings turned to Nick Mullens over Joshua Dobbs and dropped a close game at Cincinnati last Saturday. Justin Jefferson played through a chest contusion and is trying to get back on track after missing several weeks with a hamstring. 

Washington Commanders at New York Jets

Sunday, 1 p.m. ET, CBS

The Washington Commanders have dropped five straight games and are allowing a league-high 30.2 points and 384.5 yards per game. Their pass defense has struggled badly and become more vulnerable since they traded Chase Young and Montez Sweat in late October.

The New York Jets got a great performance from Zach Wilson in Week 14 and were shut out the following Sunday in Miami, with Wilson exiting early due to a concussion. Officially eliminated from playoff contention, the Jets are unlikely to risk starting Aaron Rodgers (Achilles), who could be cleared to play. 

Green Bay Packers at Carolina Panthers

Sunday, 1 p.m. ET, Fox

The Green Bay Packers have fallen flat in two losses after beating the Chiefs in a Week 13 primetime spot. They follow this road game with divisional matchups against the Vikings and Bears that could play a factor in a tight NFC wild card race. 

The Carolina Panthers scored their first win under interim head coach Matt Tabor with their defense paving the way to victory over the Falcons in a rainstorm. Carolina is averaging 155.3 rushing yards per game in three weeks under Tabor. 

Cleveland Browns at Houston Texans

Sunday, 1 p.m. ET, CBS

The Cleveland Browns came back from a 10-point deficit in the fourth quarter with Joe Flacco overcoming three early interceptions to deliver clutch passes against an improving Bears defense. Cleveland’s offensive line has been ravaged by injuries, and the team also has a few key injuries on defense. 

The Houston Texans pulled out an overtime win at Tennessee with Case Keenum subbing in for C.J. Stroud (concussion). Nico Collins (calf) also missed the game, but Dalton Schultz (hamstring) returned and Noah Brown came through as their top receiver. 

Jacksonville Jaguars at Tampa Bay Buccaneers

Sunday, 4:05 p.m. ET, CBS

The Jacksonville Jaguars have gone from huge favorites to win the AFC South to around even money after losing three straight games. Trevor Lawrence is in concussion protocol on top of his ankle injury, and the Jags have been missing key members of their secondary. 

The Tampa Bay Buccaneers produced a season-high 452 yards in a 34-20 win at Green Bay in Week 15 to maintain their lead atop the NFC South. Their defense is allowing the second-most passing yards per game (264) and ninth-fewest rushing yards per game (96) this season. 

Arizona Cardinals at Chicago Bears

Sunday, 4:25 p.m. ET, Fox

The Arizona Cardinals tried to keep pace with the juggernaut 49ers but eventually succumbed to the NFC West leaders on Sunday. They’re 2-3 since Kyler Murray returned and are averaging 21.6 points per game in those contests.  

The Chicago Bears are a few fourth-quarter plays away from winning five straight games; instead, they’re 3-2 with some of the best defensive metrics in the NFL during that span. Justin Fields has rushed for 251 yards since returning from a thumb injury, but he struggled as a passer in Cleveland last week.  

Dallas Cowboys at Miami Dolphins

Sunday, 4:25 p.m. ET, CBS

The Dallas Cowboys are 3-4 on the road and 7-0 at home this season. They’re coming off an unimpressive 31-10 loss at Buffalo in which Micah Parsons hyperextended his knee. Dallas is a long shot to win the NFC East in the latest odds. 

The Miami Dolphins blew a late 27-13 lead to the Titans in Week 14, then bounced back with a 30-0 thrashing of the Jets despite the absence of MVP candidate Tyreek Hill (ankle). Injuries along their offensive line bear monitoring ahead of this matchup. 

New England Patriots at Denver Broncos

Sunday, 8:15 p.m. ET, NFL Network 

The New England Patriots were flexed out of a Monday Night Football slot last week and validated that decision by producing just 206 yards of offense in a 27-17 home loss to the Chiefs. 

The Denver Broncos put together an incredible turnaround on defense to go 6-1 after a 1-5 start to their season. That defense couldn’t hold up in a 42-17 loss at Detroit on Saturday night. 

Las Vegas Raiders at Kansas City Chiefs

Monday, 1 p.m. ET, CBS

The Las Vegas Raiders are 3-3 under interim coach Antonio Pierce and coming off a 63-21 demolition of the Chargers that set a new record for points in a Thursday Night Football game. They gave up 31 straight points to the Chiefs in a 31-17 home loss in Week 12. 

The Kansas City Chiefs snapped a two-game skid with a 27-17 win versus the Patriots despite committing two turnovers in a second straight game. The Chiefs are looking to lock up an eighth straight AFC West title. 

New York Giants at Philadelphia Eagles

Monday, 4:30 p.m. ET, Fox

The New York Giants put together a three-game winning streak with Tommy DeVito under center, but they couldn’t keep pace in a 24-6 loss in New Orleans in Week 15. Darren Waller (hamstring) returned from a lengthy absence in that contest with the Giants holding onto slim wild card hopes. 

The Philadelphia Eagles are on a short week for this divisional matchup after their Sunday game was flexed to Monday night at Seattle. Jalen Hurts (illness) is questionable to suit up. 

Baltimore Ravens at San Francisco 49ers

Monday, 8:15 p.m. ET, ABC

The Baltimore Ravens are looking to hold onto their status as the top seed in the AFC, while the Niners lead the NFC. Kyle Hamilton (knee) was able to play through injury and help their defense in a 23-7 win in Jacksonville on Sunday night.

The San Francisco 49ers have been the best team in the NFL since their bye week and are the top Super Bowl 58 favorites, with Brock Purdy leading in MVP odds. Christian McCaffrey has popped up on the injury report with knee tendinitis.

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