The 2023-24 NFL season is officially underway, and sportsbooks have released and updated odds on every upcoming game in Week 2. The second week of play in the NFL season brings some interesting matchups, including the Baltimore Ravens hitting the road without JK Dobbins, who is out for the season with a torn Achilles, for an AFC North matchup with the Cincinnati Bengals.
In other Week 2 action, the Dallas Cowboys host a New York Jets team that will be without injured QB Aaron Rodgers, also out for the rest of the season with an Achilles injury. In the AFC East, the New England Patriots host the Miami Dolphins on Sunday Night Football.
Read on for a closer look at Week 2 betting odds from the best NFL betting sites, including spreads, moneylines, and point totals, along with injury updates for every NFL team.
NFL Week 2 odds: Best available point spreads, moneylines, and totals
| Date | Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|---|
| Thursday, Sept. 14, 8:15 p.m. ET | Vikings @ Eagles | O/U | ||
| Sunday, Sept. 17, 1 p.m. ET | Ravens @ Bengals | O/U | ||
| Sunday, Sept. 17, 1 p.m. ET | Seahawks @ Lions | O/U | ||
| Sunday, Sept. 17, 1 p.m. ET | Colts @ Texans | O/U | ||
| Sunday, Sept. 17, 1 p.m. ET | Bears @ Buccaneers | O/U | ||
| Sunday, Sept. 17, 1 p.m. ET | Chiefs @ Jaguars | O/U | ||
| Sunday, Sept. 17, 1 p.m. ET | Packers @ Falcons | O/U | ||
| Sunday, Sept. 17, 1 p.m. ET | Raiders @ Bills | O/U | ||
| Sunday, Sept. 17, 1 p.m. ET | Chargers @ Titans | O/U | ||
| Sunday, Sept. 17, 4:05 p.m. ET | 49ers @ Rams | O/U | ||
| Sunday, Sept. 17, 4:05 p.m. ET | Giants @ Cardinals | O/U | ||
| Sunday, Sept. 17, 4:25 p.m. ET | Jets @ Cowboys | O/U | ||
| Sunday, Sept. 17, 4:25 p.m. ET | Commanders @ Broncos | O/U | ||
| Sunday, Sept. 17, 6:20 p.m. ET | Dolphins @ Patriots | O/U | ||
| Monday, Sept. 18, 7:15 p.m. ET | Saints @ Panthers | O/U | ||
| Monday, Sept. 18, 8:15 p.m. ET | Browns @ Steelers | O/U |
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NFL Week 2 matchups and odds
Minnesota Vikings at Philadelphia Eagles
Thursday, 8:15 p.m. ET
- Spread: Vikings , Eagles
- Moneyline: Vikings , Eagles
- Total:
The Minnesota Vikings put up some big passing numbers in Week 1 but still lost 20-17 at home against the Buccaneers. Kirk Cousins threw for 344 yards and two touchdowns with one interception, but the Vikings sputtered late and turned the ball over three times in the loss. The team lost C Garrett Bradbury early in the game to an apparent back injury, and he has since been ruled out for Week 2. Minnesota also had injuries elsewhere on the offensive line, with T Christian Darrisaw still questionable for this game.
The Philadelphia Eagles got a 25-20 win on the road over the Patriots to start the season. MVP candidate Jalen Hurts threw for 170 yards and one touchdown while running for another 37 yards. DT Fletcher Cox did not practice on Monday due to an issue with his ribs and is listed as questionable. RB Kenneth Gainwell, S Reed Blankenship, and CB James Bradberry are all out for Thursday night’s game.
Baltimore Ravens at Cincinnati Bengals
Sunday, 1 p.m. ET
- Spread: Ravens , Bengals
- Moneyline: Ravens , Bengals
- Total:
The Baltimore Ravens pulled away in the second half to beat the Texans at home in Week 1, 25-9. Lamar Jackson threw for 169 yards with one interception and also led the team in rushing with 38 yards on six carries. RB J.K. Dobbins is out for the season with a torn Achilles tendon, a major blow to the team. The offensive line is also banged up, with starting C Tyler Linderbaum dealing with an ankle injury and T Ronnie Stanley hampered by a knee sprain. Both are week-to-week and may miss Week 2, according to coach John Harbaugh. Additionally, S Marcus Williams is dealing with a pectoral issue and could be out for some time, Harbaugh said.
The Cincinnati Bengals struggled to get anything going offensively in a 24-3 Week 1 loss to the Browns. Joe Burrow went 14-of-31 for 82 yards and seemed to struggle with the wet conditions just days after signing a contract that made him the NFL’s highest-paid player. Burrow’s outlook to win the NFL MVP award took a hit in the aftermath of the game, and he’s now at odds. DE Joseph Ossai is back at practice this week, and there’s hope he could return from injury in time for this AFC North divisional matchup.
Seattle Seahawks at Detroit Lions
Sunday, 1 p.m. ET
- Spread: Seahawks , Lions,
- Moneyline: Seahawks , Lions
- Total:
The Seattle Seahawks fell at home against the Rams 30-13 to start the season on Sunday. Geno Smith threw for 112 yards and one touchdown, but Seattle was shut out in the second half and gained only 180 total yards while giving up 426. One big concern was WR Taylor Lockett, who was evaluated for a concussion after hauling in two passes for 10 yards before being knocked out of the game. Seattle also saw injuries to both starting tackles on its offensive line. RT Abe Lucas will miss at least four games with a knee injury. LT Charles Cross is dealing with a toe issue, but may still play Sunday. Head coach Pete Carroll did say there was a chance that top draft pick Devon Witherspoon could return from injury to make his Seahawks debut this week.
The Detroit Lions notched a big win as underdogs on the road against the defending Super Bowl champion Chiefs last Thursday. The Lions seem intent on establishing the running game behind one of the league’s best offensive lines, but they also got solid play from QB Jared Goff, who threw for 253 yards and one touchdown. The Lions remain the top favorite to win the NFC North, but they are dealing with injuries in the defensive backfield, as both Emmanuel Moseley and Brian Branch are questionable for Week 2. T Tyler Decker was seen in a walking boot earlier this week.
Indianapolis Colts at Houston Texans
Sunday, 1 p.m. ET
- Spread: Colts , Texans
- Moneyline: Colts , Texans
- Total:
The Indianapolis Colts lost their opening game for the 10th straight year, going down 31-21 to the Jaguars at home. Rookie QB Anthony Richardson threw for 223 yards with one TD through the air and another on the ground, but the fourth overall draft pick left the game late with a bruised knee. Richardson said after the game that the injury isn’t serious, but the team inititally listed him as questionable for Week 2. The offensive line also suffered injuries, with T Braden Smith and G Quenton Nelson both missing practice this week. TE Drew Ogletree also sat out with a concussion this week, but RB Zach Moss has been upgraded and is back to regular duty.
The Houston Texans failed to score a touchdown in a 25-9 Week 1 loss on the road against the Baltimore Ravens. Rookie QB CJ Stroud went 28-for-44 with 242 yards through the air in his first NFL game, but Houston couldn’t find the end zone. Houston has two injuried safeties causing some concern, as Jalen Pitre left the game with a chest injury, and Jimmie Ward is dealing with a hip issue. Both are questionable for Week 2. Altogether the Texans had 11 players miss practice time with injuries this week.
Chicago Bears at Tampa Bay Buccaneers
Sunday, 1 p.m. ET
- Spread: Bears , Buccaneers
- Moneyline: Bears , Buccaneers
- Total:
The Chicago Bears went down at home 38-20 against the Packers on Sunday. Justin Fields led the team in both passing and rushing, but the Bears lost two turnovers and gave up four sacks while letting the Packers pull away in the second half. Bears S Jaquan Brisker left the game with an upper body injury, and his status is unclear for the Week 2 matchup. CB Kyler Gordon is questionable with a hand injury.
The Tampa Bay Buccaneers recovered from a rocky start to begin the season with a 20-17 road win over the Vikings. QB Baker Mayfield did a good job of protecting the ball, throwing for 173 yards and two touchdowns, and Tampa Bay didn’t turn the ball over once. The team’s two top draft picks — RG Cody Mauch and DL Calijah Kancey — were both questionable to play but made their NFL debuts in the win. Kancey is still questionable for Week 2, and OLB Lavonte David has entered the league’s concussion protocol.
Kansas City Chiefs at Jacksonville Jaguars
Sunday, 1 p.m. ET
- Spread: Chiefs , Jaguars
- Moneyline: Chiefs , Jaguars
- Total:
The Kansas City Chiefs stumbled in Week 1 with a 21-20 loss at home to the Lions. Patrick Mahomes threw for 226 yards and two touchdowns but was missing tight end Travis Kelce due to a knee injury. Kelce is “progressing,” according to head coach Andy Reid, and was back at practice this week in a limited role. DT Chris Jones has ended his holdout, signing a one-year contract with the Chiefs. He is also back at practice and is expected to play in Week 2.
The Jacksonville Jaguars started the season with a 31-21 road win against the Colts on Sunday, ending a five-game losing streak in Indianapolis. QB Trevor Lawrence threw for 242 yards with two TDs and one interception. Jacksonville lost RG Brandon Scherff and CB Gregory Junior to injury during the game. Both missed time in practice this week and are day-to-day. DB Antonio Johnson is likely out this week.
Green Bay Packers at Atlanta Falcons
Sunday, 1 p.m. ET
- Spread: Packers , Falcons
- Moneyline: Packers , Falcons
- Total:
The Green Bay Packers began the season with a 38-20 road win over the NFC North rival Bears on Sunday. Jordan Love embraced his role as the team’s unquestioned starter, throwing for 245 yards with three TDs as the Packers racked up 28 points in the second half. Aaron Jones rushed for 41 yards on nine carries and had two TDs — one on the ground and one through the air — but the team has listed him as questionable for Week 2 after he left with a hamstring injury. LB Quay Walker has entered the concussion protocol.
The Atlanta Falcons got a 24-10 home win over the Panthers to start the season. The team’s top draft pick — Bijan Robinson — had a solid performance in his NFL debut, averaging 5.6 yards per carry and hauling in six passes, including one for a touchdown. Atlanta leaned heavily on the running game, with QB Desmond Ridder attempting only 18 passes and completing 15 of them for 115 yards and a touchdown. CB Jeff Okudah is questionable with a foot injury.
Las Vegas Raiders at Buffalo Bills
Sunday, 1 p.m. ET
- Spread: Raiders , Bills
- Moneyline: Raiders , Buffalo
- Total:
The Las Vegas Raiders pulled out a 17-16 victory on the road against the Broncos on Sunday. In his first game with the Raiders, Jimmy Garoppolo threw for 200 yards and two TDs, including the go-ahead score to Jakobi Meyers, who is questionable for Week 2 due to a concussion. The team has also listed DE Chandler Jones as questionable for personal reasons, and WR DeAndre Carter missed practice with a knee injury.
The Buffalo Bills lost to the Jets on Monday Night Football, going down 22-16 in overtime. Josh Allen threw three interceptions along with 236 yards and one TD through the air. Stefon Diggs caught 10 passes for 102 yards and a touchdown, but the Bills turned the ball over four times and Buffalo’s special teams gave up a 65-yard punt return for the game-winning touchdown in overtime. Linebackers Von Miller and Baylon Specter are both expected to be out until Week 5.
Los Angeles Chargers at Tennessee Titans
Sunday, 1 p.m. ET
- Spread: Chargers , Titans
- Moneyline: Chargers , Titans
- Total:
The Los Angeles Chargers lost a shootout at home against the Dolphins on Sunday, 36-34. Justin Herbert went 23-of-33 with 228 yards and one TD. The Chargers’ running game was particularly strong in the game, but RB Austin Ekeler is questionable for Week 2 with an ankle injury. That concern at running back was apparently enough to convince the team to quickly sign Jarret Patterson, formerly of the Commanders. Receiver Mike Williams was hit hard in the first half and received evaluation for a head injury.
The Tennessee Titans fell 16-15 on the road against the Saints on Sunday. Ryan Tannehill was picked off three times, and the Titans were kept out of the end zone all day while converting just two third downs on 12 tries. Titans kicker Nick Folk was a perfect five-for-five on field goals, including a 50-yarder. S Amani Hooker is questionable for Week 2 with a concussion, while T Dillon Radunz is questionable due to a knee injury. WR DeAndre Hopkins did not practice this week due to an ankle injury.
San Francisco 49ers at Los Angeles Rams
Sunday, 4:05 p.m. ET
- Spread: 49ers , Rams
- Moneyline: 49ers , Rams
- Total:
The San Francisco 49ers dominated the Steelers for a 30-7 road win to start the season on Sunday. Brock Purdy threw for 220 yards and two TDs, while Christian McCaffrey got off to a strong start with 152 yards on the ground and one touchdown. DE Robert Beal Jr. and CB Daryl Luter Jr. are both injured and expected to return for Week 5. TE George Kittle had been dealing with a groin issue, but he practiced fully this week.
The Los Angeles Rams got a 30-13 win on the road against the Seahawks to open the season. Matthew Stafford had a good return with 334 yards passing and 24 completions on 38 attempts. Kyren Williams led the way rushing, gaining 52 yards with two TDs on the ground. The team expects WR Cooper Kupp and TE Hunter Long to be out until Week 5.
New York Giants at Arizona Cardinals
Sunday, 4:05 p.m. ET
- Spread: Giants , Cardinals
- Moneyline: Giants , Cardinals
- Total:
The New York Giants endured a 40-0 blowout loss at home and a raft of injuries against the Cowboys on Sunday night. The first quarter alone saw a blocked field goal returned for a touchdown, as well as a Daniel Jones pass picked off and returned for a TD. Jones finished with 104 yards passing and two interceptions, while the Giants’ offensive line gave up seven sacks and struggled with penalties. New York exited the game with at least nine players questionable for Week 2, including injuries to offensive tackles Andrew Thomas and Matt Peart. Peart was back in a limited fashion this week, but Thomas did not practice this week and could be out for longer.
The Arizona Cardinals showed some signs of life but ultimately lost 20-16 on the road against the Commanders on Sunday. The Arizona offense scored just three points in the second half, and QB Joshua Dobbs lost a key fumble late, leading to defeat in head coach Jonathan Gannon’s first game leading the Cardinals. T Kelvin Beachum is questionable for Week 2, adding to Arizona’s pass protection concerns.
New York Jets at Dallas Cowboys
Sunday, 4:25 p.m. ET
- Spread: Jets , Cowboys
- Moneyline: Jets , Cowboys
- Total:
The New York Jets got a dramatic overtime win thanks to a punt return for a touchdown by Xavier Gipson to beat the Bills 22-16 on Monday Night Football. The bad news is that the team lost QB Aaron Rodgers almost as soon as the game started, and if an MRI confirms a torn Achilles, he’ll likely be out for the season. The Jets went with Zach Wilson under center in Rodgers’ absence. Wilson threw for 140 yards with one TD and one interception, while Breece Hall picked up the slack in the running game, rushing for 127 yards on just 10 carries.
The Dallas Cowboys hammered the Giants for a 40-0 road win on Sunday night. Dak Prescott threw for 143 yards on 23 passing attempts, and Tony Pollard ran for two TDs and 70 yards on 14 carries. S Donovan Wilson missed Week 1 with a calf injury and is questionable for Week 2. T Tyler Smith is also questionable for Sunday’s game.
Washington Commanders at Denver Broncos
Sunday, 4:25 p.m. ET
- Spread: Commanders , Broncos
- Moneyline: Commanders , Broncos
- Total:
The Washington Commanders got a scare at home against a Cardinals team that’s expected to be among the worst in the league, but they pulled it together in the second half for a 20-16 victory in the first game for the team’s new ownership. Sam Howell threw for 202 yards with one TD and one interception, while Brian Robinson led the team in rushing despite only gaining 59 yards on 19 carries. Howell was evaluated for a concussion during the game but was cleared to return. CB Jartavius Martin is questionable with a concussion and did not practice, while DE Chase Young is questionable due to a neck injury.
The Denver Broncos couldn’t hold the lead at home against the Raiders on Sunday and started the season with a 17-16 loss. Russell Wilson had a good day under center, throwing for 177 yards and two TDs with no interceptions. Broncos S Caden Sterns was carted off the field with an apparent knee injury in the first half and is doubtful for Week 2. TE Greg Dulcich did not practice and is doubtful for the game due to a hamstring issue.
Miami Dolphins at New England Patriots
Sunday, 6:20 p.m. ET
- Spread: Dolphins , Patriots
- Moneyline: Dolphins , Patriots
- Total:
The Miami Dolphins got off to a winning start with a 36-34 victory over the Chargers in a dramatic Week 1 game that saw multiple lead changes. The passing game accounted for almost the entire Miami offense, as Tua Tagovailoa threw for 466 yards and three TDs with one interception. The Dolphins amassed over 500 yards in total offense, but only 70 of that came on the ground. Dolphins T Terron Armstead sat out and is questionable for Week 2. TE Julian Hill and DB Elijah Campbell are also questionable for the game.
The New England Patriots went down 25-20 at home to start the season against the Eagles. QB Mac Jones threw for 316 yards with three TDs and one interception, but the Patriots struggled to get the running game going and settled for just six points in the second half. New England’s offensive line is banged up headed into Week 2, with guards Mike Onwenu and Cole Strange both questionable due to lower body injuries. T Trent Brown missed practice this week due to a concussion.
New Orleans Saints at Carolina Panthers
Monday, 7:15 p.m. ET
- Spread: Saints , Panthers
- Moneyline: Saints , Panthers
- Total:
The New Orleans Saints pulled out a 16-15 victory over the Titans at home to open the season on Sunday. Derek Carr threw for 305 yards with one TD and one interception in his first game under center for New Orleans, and WR Chris Olave caught eight passes for 112 yards. RB Kendre Miller and DB J.T. Gray are both questionable for Week 2. G Brady Christenson is out for the season due to a biceps injury. Undrafted rookie Nash Jensen is set to take his place.
The Carolina Panthers suffered a road loss by a score of 24-10 against the Falcons on Sunday. Top draft pick Bryce Young threw for 146 yards and one TD, but he was picked off twice in a rocky debut for his first NFL game. Miles Sanders led the Panthers on the ground with 72 yards rushing on 18 carries. The Panthers lost CB Jaycee Horn to a leg injury in the first half, and he is doubtful for Week 2.
Cleveland Browns at Pittsburgh Steelers
Monday, 8:15 p.m.
- Spread: Browns , Steelers
- Moneyline: Browns , Steelers
- Total:
The Cleveland Browns opened the season with a statement win at home against the Bengals — 24-3 in wet, rainy conditions. Deshaun Watson threw for 154 yards with one TD and one interception, while Nick Chubb ran for 104 yards on 18 carries. Cleveland RT Jack Conklin left the game with a knee injury in the first half and was replaced by rookie lineman Dawand Jones. Conklin has since been ruled out with ACL and MCL injuries.
The Pittsburgh Steelers sputtered out the gates in a 30-7 home loss to open the season against the 49ers on Sunday, enduring a rash of injuries in the process. Receiver Diontae Johnson left the game early after taking a hard shot and is doubtful for Week 2. RT Chukwuma Okorafor has entered the league’s concussion protocol and is also questionable for Week 2. Pittsburgh could also be missing TE Pat Friermuth, who caught a touchdown on Sunday but left with a chest injury and is listed as questionable. DL Cam Heyward is out for multiple weeks with a groin injury.
